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• W2683567139 abstract "ObjectiveTo determine whether serum fructosamine correlates with glycemic control and clinical outcomes in patients being screened for cystic fibrosis-related diabetes (CFRD).MethodsFructosamine and percent predicted forced expiratory volume in 1 s (FEV1) were measured in patients undergoing a 2 h oral glucose tolerance test (OGTT) for CFRD screening. Fractional serum fructosamine (FSF) was calculated as fructosamine/total protein.ResultsFSF exhibited a positive correlation with 2 h OGTT results (r2 = 0.3201, p = 0.009), and ROC curve analysis suggested that FSF can identify patients with an abnormal OGTT (AUC = 0.840, p = 0.0002). FSF also exhibited a negative correlation with FEV1 (r2 = 0.3732, p = 0.035). Patients with FSF ≥ 3.70 μmol/g had significantly lower FEV1 (median 47%) compared to those with FSF < 3.70 μmol/g (median 90%; p = 0.015).ConclusionsFSF correlated with both OGTT results and FEV1, and reliably identified patients with abnormal OGTT results. This simple blood test shows potential as an effective tool in CFRD screening." @default.
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• W2683567139 date "2018-01-01" @default.
• W2683567139 modified "2023-10-16" @default.
• W2683567139 title "The use of fructosamine in cystic fibrosis-related diabetes (CFRD) screening" @default.
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• W2683567139 doi "https://doi.org/10.1016/j.jcf.2017.05.010" @default.
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