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- W268519 abstract "Murine peritoneal macrophages were treated with interferon-gamma (IFN-gamma) or tumor necrosis factor-alpha (TNF). Measurements of changes in acid phosphatase and beta-glucuronidase levels were made as an indication of activation by cytokine treatment. IFN-gamma or TNF-gamma treatment resulted in a significant increase in the activities of both enzymes measured in the cell lysates. This increase was observable after 6 h of incubation, but reached its maximum level after 24 h of incubation. The effect of the treatment of the cells with both cytokines together was additive. No synergistic effect of addition of both cytokines on the enzyme levels was observed." @default.
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- W268519 date "1989-02-01" @default.
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- W268519 title "Effects of Interferon-γ and Tumor Necrosis Factor-α on Macrophage Enzyme Levels" @default.
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- W268519 doi "https://doi.org/10.1089/jir.1989.9.1" @default.
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