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- W2692591569 abstract "Stimuli-responsive polymers that undergo physical or chemical changes in response to environmental variations, when integrated into devices, can behave like living organisms to “sense and react” and produce intended responses once stimulated. Of all the different stimuli, change in the redox state is particularly attractive to polymer scientists because of well-documented redox variations in the body and the close association of unusual levels of redox potentials in certain diseases. Hydrogels, which are highly hydrophilic three-dimensional network of polymers, have always been regarded as one of the most promising biomaterials composite for biomedical applications, and redox-responsive hydrogels have been frequently employed in areas such as tissue engineering and drug delivery. Among the several different polymers used to prepare hydrogels, poly(amido amine)s being biocompatible and highly versatile have gained significant attention in recent years. Therefore, in this chapter, we would like to address the potential of poly(amido amine)s-based redox-responsive hydrogels. The synthesis mechanism of poly(amido amine)s via the Michael addition polymerization of bisacrylamide, such as N,N-cystaminebis(acrylamide), and trifunctional amines, such as 1-(2-aminoethyl)piperidine or 4-(aminomethyl)piperidine, will be discussed in detail. Different techniques to prepare the redox-responsive hydrogels will also be presented. Innovative approaches to nano/microgels, which possess both the advantageous properties of nanoparticles and hydrogels, are also highlighted. Lastly, the potential of redox-responsive hydrogels will be demonstrated in various biomedical applications." @default.
- W2692591569 created "2017-06-30" @default.
- W2692591569 creator A5018742393 @default.
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- W2692591569 date "2017-01-01" @default.
- W2692591569 modified "2023-10-16" @default.
- W2692591569 title "Redox-responsive hydrogels" @default.
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- W2692591569 doi "https://doi.org/10.1016/b978-0-08-101914-6.00002-8" @default.
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