Matches in SemOpenAlex for { <https://semopenalex.org/work/W2693560003> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2693560003 endingPage "106" @default.
- W2693560003 startingPage "106" @default.
- W2693560003 abstract "Introduction Acute myeloid leukemia (AML) is a heterogenous disorder that results from a block in the differentiation of hematopoietic progenitor cells along with uncontrolled proliferation. Cytogenetics represents the most valuable predictor for a poor outcome in patients with AML, and the cytogenetic profile of AML at diagnosis consistently remains a highly influential prognostic factor. Of these cytogenetic aberrations, patients with complex karyotype anomalies show very low complete remission rates and short leukemia-free and overall survival. Case presentation We report a case of AML in a 50-year-old female patient who presented with morphologic and immunophenotypic features of AML-M1. The patient's karyotyping and fluorescence in-situ hybridization of cultured bone marrow cells revealed a unique complex karyotype: 49, XX, +1, +8, +21. The patient's condition deteriorated rapidly and she died shortly after induction from fatal infectious complications.Conclusion Reports of trisomy 1 in AML are rare, and, to the best of our knowledge, the present case is the only one reported with the occurrence of trisomy 1 in addition to trisomy 8 and 2. Treatment outcomes of complex karyotype AML patients receiving chemotherapy are very poor; the yet unreported complex karyotype observed in this case seems to be correlated with an adverse prognosis. Single case reports as well as large scale studies are necessary to provide further insights on karyotypic changes taking place in human malignancies." @default.
- W2693560003 created "2017-06-30" @default.
- W2693560003 creator A5039478832 @default.
- W2693560003 creator A5041194593 @default.
- W2693560003 creator A5045333996 @default.
- W2693560003 creator A5061583898 @default.
- W2693560003 date "2016-01-01" @default.
- W2693560003 modified "2023-10-01" @default.
- W2693560003 title "Acute myeloid leukemia, M1 with trisomy 1, 8, and 21: a case report of a rare complex karyotype" @default.
- W2693560003 cites W1534965621 @default.
- W2693560003 cites W1950612017 @default.
- W2693560003 cites W1981570437 @default.
- W2693560003 cites W1983857367 @default.
- W2693560003 cites W2003646197 @default.
- W2693560003 cites W2024483536 @default.
- W2693560003 cites W2026510224 @default.
- W2693560003 cites W2034295250 @default.
- W2693560003 cites W2036163692 @default.
- W2693560003 cites W2059513964 @default.
- W2693560003 cites W2062937743 @default.
- W2693560003 cites W2067954431 @default.
- W2693560003 cites W2114441791 @default.
- W2693560003 cites W2159738043 @default.
- W2693560003 cites W2162700652 @default.
- W2693560003 cites W2735652847 @default.
- W2693560003 doi "https://doi.org/10.4103/1110-1067.186415" @default.
- W2693560003 hasPublicationYear "2016" @default.
- W2693560003 type Work @default.
- W2693560003 sameAs 2693560003 @default.
- W2693560003 citedByCount "2" @default.
- W2693560003 countsByYear W26935600032021 @default.
- W2693560003 countsByYear W26935600032022 @default.
- W2693560003 crossrefType "journal-article" @default.
- W2693560003 hasAuthorship W2693560003A5039478832 @default.
- W2693560003 hasAuthorship W2693560003A5041194593 @default.
- W2693560003 hasAuthorship W2693560003A5045333996 @default.
- W2693560003 hasAuthorship W2693560003A5061583898 @default.
- W2693560003 hasConcept C104317684 @default.
- W2693560003 hasConcept C126322002 @default.
- W2693560003 hasConcept C142724271 @default.
- W2693560003 hasConcept C143998085 @default.
- W2693560003 hasConcept C174475383 @default.
- W2693560003 hasConcept C2776229224 @default.
- W2693560003 hasConcept C2776611710 @default.
- W2693560003 hasConcept C2776694085 @default.
- W2693560003 hasConcept C2778461978 @default.
- W2693560003 hasConcept C2778729363 @default.
- W2693560003 hasConcept C2779282312 @default.
- W2693560003 hasConcept C2780365373 @default.
- W2693560003 hasConcept C30481170 @default.
- W2693560003 hasConcept C53226629 @default.
- W2693560003 hasConcept C54355233 @default.
- W2693560003 hasConcept C71924100 @default.
- W2693560003 hasConcept C86803240 @default.
- W2693560003 hasConceptScore W2693560003C104317684 @default.
- W2693560003 hasConceptScore W2693560003C126322002 @default.
- W2693560003 hasConceptScore W2693560003C142724271 @default.
- W2693560003 hasConceptScore W2693560003C143998085 @default.
- W2693560003 hasConceptScore W2693560003C174475383 @default.
- W2693560003 hasConceptScore W2693560003C2776229224 @default.
- W2693560003 hasConceptScore W2693560003C2776611710 @default.
- W2693560003 hasConceptScore W2693560003C2776694085 @default.
- W2693560003 hasConceptScore W2693560003C2778461978 @default.
- W2693560003 hasConceptScore W2693560003C2778729363 @default.
- W2693560003 hasConceptScore W2693560003C2779282312 @default.
- W2693560003 hasConceptScore W2693560003C2780365373 @default.
- W2693560003 hasConceptScore W2693560003C30481170 @default.
- W2693560003 hasConceptScore W2693560003C53226629 @default.
- W2693560003 hasConceptScore W2693560003C54355233 @default.
- W2693560003 hasConceptScore W2693560003C71924100 @default.
- W2693560003 hasConceptScore W2693560003C86803240 @default.
- W2693560003 hasIssue "2" @default.
- W2693560003 hasLocation W26935600031 @default.
- W2693560003 hasOpenAccess W2693560003 @default.
- W2693560003 hasPrimaryLocation W26935600031 @default.
- W2693560003 hasRelatedWork W1517612201 @default.
- W2693560003 hasRelatedWork W1978238000 @default.
- W2693560003 hasRelatedWork W2041569392 @default.
- W2693560003 hasRelatedWork W2042363973 @default.
- W2693560003 hasRelatedWork W2055544080 @default.
- W2693560003 hasRelatedWork W2066107675 @default.
- W2693560003 hasRelatedWork W2073835741 @default.
- W2693560003 hasRelatedWork W2075866438 @default.
- W2693560003 hasRelatedWork W2403715258 @default.
- W2693560003 hasRelatedWork W2693560003 @default.
- W2693560003 hasVolume "41" @default.
- W2693560003 isParatext "false" @default.
- W2693560003 isRetracted "false" @default.
- W2693560003 magId "2693560003" @default.
- W2693560003 workType "article" @default.