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- W2695681346 abstract "Almost all nanofluidic devices for biopolymer analysis have been limited by one or two confining structural dimensions or the application of external forces for biopolymer manipulation, which has restricted the scope of related lab-on-achip technology. Here, a nanofluidic channel with a three dimensional (3D) “staircase” depth profile across its width was used to control and measure the behavior of individual DNA molecules, which “descended” the confining staircase via “entropophoresis” effected by interactions between the DNA molecules and the nanofluidic step edges. Thus, the nanofabricated staircase enabled complex structural control over DNA transport and conformation without the application of external forces." @default.
- W2695681346 created "2017-06-30" @default.
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- W2695681346 date "2010-10-04" @default.
- W2695681346 modified "2023-09-23" @default.
- W2695681346 title "Nanoslinky: DNA Entropophoresis Down a Nanofluidic Staircase | NIST" @default.
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