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- W2697210530 abstract "The superficial skin tissue makes up mainly of 4 layers, stratum corneum, epidermis, dermis and hypodermis. Skin wrinkles could cause water content and bio-mechanical characteristics distributed in these layers to be changed by aging and ultraviolet exposure, and son on. It is, therefore, necessary to develop a tomographically and non-invasively measuring method of water content and mechanical characteristics, as well as to reveal wrinkle mechanism from these relationships. Recently, Optical Coherence Tomography (OCT) has attracted biomedical attention as an in vivo clinical diagnostic manner. The authors proposed Multi-Functional OCT, i.e. 2-Color Optical Coherence Moisturegraphy (2C-OCM) and 3-Dimensional Optical Coherence Straingraphy (3D-OCSA), as a novel tomographic visualizing technique of water content and micro-biomechanics, respectively. In this study, both proposed methods were in vivo applied to human's finger skin so as to evaluate the applicability to skin care and cosmetic research. As a result, 2C-OCM can visualize high and low water content around epidermis and stratum corneum, respectively. While, 3D-OCSA can discover negative strain, i.e. compressive deformation, distributed at the boundary between stratum corneum and epidermis. Consequently, it was confirmed that Multi-Functional OCT is highly effective to micro-biomechanical diagnosis of skin tissue, for the purpose of revealing the skin wrinkle mechanism." @default.
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- W2697210530 date "2011-01-01" @default.
- W2697210530 modified "2023-09-25" @default.
- W2697210530 title "J022014 Development Study on Tomographically Visualizing Method of Water Content and Mechanical Strain in Skin Tissue using Low Coherence Interferometer" @default.
- W2697210530 doi "https://doi.org/10.1299/jsmemecj.2011._j022014-1" @default.
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