Matches in SemOpenAlex for { <https://semopenalex.org/work/W26981288> ?p ?o ?g. }
- W26981288 endingPage "117" @default.
- W26981288 startingPage "83" @default.
- W26981288 abstract "This chapter describes the structural variations in cholinergic ligands. Comparative pharmacological and biochemical studies of chemically modified analogues of a particular chemical entity have been extensively used as an approach for defining the chemical nature of receptors. Rules relating the conformational and electronic requirements necessary for affinity and efficacy of a molecule in a particular receptor can sometimes be developed. The failure to produce significant structure activity relationships for cholinergic agents stems from a number of factors. The chapter reviews the various observations that have been made to date on the structures of pertinent cholinergic ligands. There is no direct evidence on the structure of a molecule at the active site of a cholinergic receptor. It is, thus, necessary to use circumstantial evidence from molecular orbital calculations, and crystallographic and solution studies to learn about the nature of substrate at a receptor site until direct observations of the receptor–substrate complex can be made." @default.
- W26981288 created "2016-06-24" @default.
- W26981288 creator A5078648251 @default.
- W26981288 date "1971-01-01" @default.
- W26981288 modified "2023-09-26" @default.
- W26981288 title "STRUCTURAL VARIATIONS IN CHOLINERGIC LIGANDS" @default.
- W26981288 cites W1482684094 @default.
- W26981288 cites W1544921064 @default.
- W26981288 cites W1571052456 @default.
- W26981288 cites W1962917760 @default.
- W26981288 cites W1964904206 @default.
- W26981288 cites W1968516288 @default.
- W26981288 cites W1976182692 @default.
- W26981288 cites W1976462943 @default.
- W26981288 cites W1976866789 @default.
- W26981288 cites W1980113478 @default.
- W26981288 cites W1983250072 @default.
- W26981288 cites W1986339258 @default.
- W26981288 cites W1991571763 @default.
- W26981288 cites W1991744193 @default.
- W26981288 cites W1991887508 @default.
- W26981288 cites W1996492927 @default.
- W26981288 cites W1997674596 @default.
- W26981288 cites W1999080290 @default.
- W26981288 cites W2002892094 @default.
- W26981288 cites W2005877813 @default.
- W26981288 cites W2009828525 @default.
- W26981288 cites W2010983801 @default.
- W26981288 cites W2011782401 @default.
- W26981288 cites W2012420716 @default.
- W26981288 cites W2013395097 @default.
- W26981288 cites W2014472901 @default.
- W26981288 cites W2016183915 @default.
- W26981288 cites W2017865534 @default.
- W26981288 cites W2026417135 @default.
- W26981288 cites W2027011775 @default.
- W26981288 cites W2035145778 @default.
- W26981288 cites W2038829246 @default.
- W26981288 cites W2038920382 @default.
- W26981288 cites W2040246654 @default.
- W26981288 cites W2042278039 @default.
- W26981288 cites W2047491943 @default.
- W26981288 cites W2051417796 @default.
- W26981288 cites W2059965197 @default.
- W26981288 cites W2071389286 @default.
- W26981288 cites W2076040605 @default.
- W26981288 cites W2083490135 @default.
- W26981288 cites W2091862979 @default.
- W26981288 cites W2113524961 @default.
- W26981288 cites W2138661720 @default.
- W26981288 cites W2173051616 @default.
- W26981288 cites W2229572103 @default.
- W26981288 cites W2313150316 @default.
- W26981288 cites W2314724849 @default.
- W26981288 cites W2323950429 @default.
- W26981288 cites W2326462449 @default.
- W26981288 cites W2329723747 @default.
- W26981288 cites W2334428845 @default.
- W26981288 cites W2409711859 @default.
- W26981288 doi "https://doi.org/10.1016/b978-0-12-700450-1.50011-7" @default.
- W26981288 hasPublicationYear "1971" @default.
- W26981288 type Work @default.
- W26981288 sameAs 26981288 @default.
- W26981288 citedByCount "3" @default.
- W26981288 crossrefType "book-chapter" @default.
- W26981288 hasAuthorship W26981288A5078648251 @default.
- W26981288 hasConcept C12554922 @default.
- W26981288 hasConcept C166957645 @default.
- W26981288 hasConcept C169760540 @default.
- W26981288 hasConcept C170493617 @default.
- W26981288 hasConcept C178790620 @default.
- W26981288 hasConcept C185592680 @default.
- W26981288 hasConcept C18903297 @default.
- W26981288 hasConcept C205649164 @default.
- W26981288 hasConcept C22885893 @default.
- W26981288 hasConcept C2777289219 @default.
- W26981288 hasConcept C2993864831 @default.
- W26981288 hasConcept C32909587 @default.
- W26981288 hasConcept C55493867 @default.
- W26981288 hasConcept C71240020 @default.
- W26981288 hasConcept C80114427 @default.
- W26981288 hasConcept C86803240 @default.
- W26981288 hasConceptScore W26981288C12554922 @default.
- W26981288 hasConceptScore W26981288C166957645 @default.
- W26981288 hasConceptScore W26981288C169760540 @default.
- W26981288 hasConceptScore W26981288C170493617 @default.
- W26981288 hasConceptScore W26981288C178790620 @default.
- W26981288 hasConceptScore W26981288C185592680 @default.
- W26981288 hasConceptScore W26981288C18903297 @default.
- W26981288 hasConceptScore W26981288C205649164 @default.
- W26981288 hasConceptScore W26981288C22885893 @default.
- W26981288 hasConceptScore W26981288C2777289219 @default.
- W26981288 hasConceptScore W26981288C2993864831 @default.
- W26981288 hasConceptScore W26981288C32909587 @default.
- W26981288 hasConceptScore W26981288C55493867 @default.
- W26981288 hasConceptScore W26981288C71240020 @default.
- W26981288 hasConceptScore W26981288C80114427 @default.
- W26981288 hasConceptScore W26981288C86803240 @default.