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- W2707307488 abstract "Cyanohydrin synthesis has become a widely studied area for asymmetric synthesis. This report describes a Lewis base (binaphtholate) catalyzed reaction between aromatic aldehydes and TMSCN. Relatively low catalyst loadings (<10 mol%), with short reaction times were sufficient to give enantiomeric excesses exceeding 90% in many cases. Good results were obtained on large scale and with a minimum of solvent (5 M in some cases)." @default.
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- W2707307488 date "2005-10-25" @default.
- W2707307488 modified "2023-09-27" @default.
- W2707307488 title "Chiral Lithium Binaphtholate Aqua Complex for Cyanohydrin Synthesis" @default.
- W2707307488 doi "https://doi.org/10.1055/s-2005-916107" @default.
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