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- W2709652590 abstract "A knowledge of binding constants is crucial to theunderstanding of molecular interactions and can be useful inthe development of new drugs and effective treatments fordiseases. Many techniques have been developed for the study ofinteractions. However the capillary electrophoresis – frontalanalysis (CE FA) measures the affinity of binding partners intheir native states without immobilization or labelling of theinteracting partners. What is more the investigatedinteractions take place in a solution, which can simulatedphysiological conditions. The other advantages are very lowsample consumption, a high resolution and also it does notrequire the highly purified samples. This work deals withapplicability of CE-FA method to study of human serum albuminand different drugs interactions, the advantages anddisadvantages of this methodological approach are summarized." @default.
- W2709652590 created "2017-06-30" @default.
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- W2709652590 date "2015-09-22" @default.
- W2709652590 modified "2023-09-27" @default.
- W2709652590 title "Use of capillary electrophoresis - frontal analysis for thecharcterization of binding between biomacromolecules andligands" @default.
- W2709652590 hasPublicationYear "2015" @default.
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