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- W2711393721 abstract "In this work, we presented a novel biosensor for rapid detection of paracetamol and ascorbic acid. The novel biosensor was based on the fluorescent turn off-on of polypyrrole/graphene quantum dots (PPy/GQDs) composites. The composites exhibit strong fluorescence emission, which is dramatically enhanced as high as three times than that of pure GQDs. It is found that the fluorescence intensity of PPy/GQDs can be efficiently quenched by N-acetyl-p-benzoquinone (4-AOBQ), the oxidation product of paracetamol (PAR). And a turn-on fluorescence signal was observed when 4-AOBQ is reduced by ascorbic acid (AA). The quenched and recovered fluorescence intensity of PPy-GQDs was proportional to the concentration of PAR (0.067-233μg/L) and AA (3.33-997.5μg/L) respectively. The limit of detection is 0.022μg/L for PAR and 1.05μg/L for AA. The present method was applied to the determination of PAR and AA in human serum samples with satisfactory results." @default.
- W2711393721 created "2017-06-30" @default.
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- W2711393721 date "2017-12-01" @default.
- W2711393721 modified "2023-09-26" @default.
- W2711393721 title "Fluorescence turn-off-on probe based on polypyrrole/graphene quantum composites for selective and sensitive detection of paracetamol and ascorbic acid" @default.
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- W2711393721 doi "https://doi.org/10.1016/j.bios.2017.06.044" @default.
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