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- W271920993 abstract "Juvenile hormones (JH) are highly pleiotropic insect hormones essential for post-embryonic development. The circulating JH titer in the hemolymph of insects is influenced by enzymatic degradation, binding to JH carrier proteins, uptake and storage in target organs, but evidently also by rates of production at its site of synthesis, the corpora allata (CA). The multiple processes in which JH is involved alongside the critical significance of JH in insect development emphasize the importance for elucidating the control of JH production. Production of JH in CA cells is regulated by different factors: by neurotransmitters, such as dopamine and glutamate, but also by allatoregulatory neuropeptides originating from the brain and axonally transported to the CA where they bind to their G protein-coupled receptors (GPCRs). Different classes of allatoregulatory peptides exist which have other functions aside from acting as influencers of JH production. These pleiotropic neuropeptides regulate different processes in different insect orders. In this mini-review, we will give an overview of allatotropins and allatostatins, and their recently characterized GPCRs with a view to better understand their modes of action and different action sites." @default.
- W271920993 created "2016-06-24" @default.
- W271920993 creator A5004762737 @default.
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- W271920993 creator A5043626304 @default.
- W271920993 creator A5074485304 @default.
- W271920993 date "2015-09-01" @default.
- W271920993 modified "2023-09-26" @default.
- W271920993 title "The pleiotropic allatoregulatory neuropeptides and their receptors: A mini-review" @default.
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