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- W271929168 abstract "背景当母体免疫球蛋白G(IgG)抗体进入胎儿循环并破坏新生儿嗜中性粒细胞时,发生新生儿同种免疫嗜中性粒细胞减少症(NAN)。抗体是否是特异性针对嗜中性粒细胞抗原HNA-1c(SH)导致NAN尚不清楚,因为在已报道的4例中有3例出现其他特异性中性粒细胞抗原。本文报道5例NAN,在母亲血清中仅检测到抗HNA-1c。研究设计与方法用免疫荧光流式细胞仪(FCI)和单克隆抗体(MoAb)同相抗原(MAIGA)试验检测HNA-1c抗体。用DNA等位基因特异性聚合酶链式反应做HNA-1c基因分型。" @default.
- W271929168 created "2016-06-24" @default.
- W271929168 creator A5059390749 @default.
- W271929168 date "2006-05-20" @default.
- W271929168 modified "2023-09-25" @default.
- W271929168 title "由于母体针对中性粒细胞同种抗原HNA-1c(SH)的免疫球蛋白G抗体引起新生儿同种免疫中性粒细胞减少症:5例报告" @default.
- W271929168 hasPublicationYear "2006" @default.
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