Matches in SemOpenAlex for { <https://semopenalex.org/work/W272141240> ?p ?o ?g. }
- W272141240 endingPage "148" @default.
- W272141240 startingPage "125" @default.
- W272141240 abstract "Due to their challenging/disruptive daytime behaviors, children and youth with fetal alcohol spectrum disorders (FASDs) are at high risk for multiple medication prescriptions. Here, we describe how undiagnosed chronic sleep problems paved the pathway for overmedication and polypharmacy in adolescents with FASDs: prescription of multiple, off-label, and concurrent pharmaceutical medications. We analyzed the challenging/disruptive sleep and wake behaviors and medication history of 17 adolescent patients with a pharmacotherapy timeline capturing (1) the medications and order of prescriptions and (2) the age at the time of first prescription. An in-depth case report demonstrates how missed sleep problems led to a diagnosis and medication cascade, impacting the life and development of the patient. All patients presented with chronic insomnia and fulfilled the diagnostic criteria for familial Willis Ekbom disease (restless legs syndrome). 11/17 had additional clinical signs of sleep-disordered breathing, and 14/17 showed excessive daytime behaviors (sleepiness and/or hyperactive-like behaviors to fight fatigue/sleepiness). The medication analysis revealed two patterns in prescription strategies: (a) targeting sleep problems with melatonin, second-generation antipsychotics, and/or combination of both (10/17) and (b) targeting hyperactive-like daytime behaviors with a psychostimulant (7/10). In addition, many medications were prescribed in combination and at alarmingly young ages. Based on our findings, we suggest assessment of sleep before any assessment of challenging/disruptive daytime behaviors and prescription of psychotropic medications. This observation raises the question to what degree children with neurodevelopmental conditions are subject to overmedication due to a missed underlying condition." @default.
- W272141240 created "2016-06-24" @default.
- W272141240 creator A5005444129 @default.
- W272141240 creator A5018889796 @default.
- W272141240 creator A5033996103 @default.
- W272141240 creator A5036175961 @default.
- W272141240 creator A5041307807 @default.
- W272141240 creator A5041774544 @default.
- W272141240 date "2015-01-01" @default.
- W272141240 modified "2023-09-25" @default.
- W272141240 title "Pathways to Overmedication and Polypharmacy" @default.
- W272141240 cites W126321052 @default.
- W272141240 cites W194558777 @default.
- W272141240 cites W1964060547 @default.
- W272141240 cites W1972618119 @default.
- W272141240 cites W1975946728 @default.
- W272141240 cites W1975957471 @default.
- W272141240 cites W1997010346 @default.
- W272141240 cites W1999095097 @default.
- W272141240 cites W2004348408 @default.
- W272141240 cites W2009834420 @default.
- W272141240 cites W2013091814 @default.
- W272141240 cites W2031279085 @default.
- W272141240 cites W2034105422 @default.
- W272141240 cites W2036713838 @default.
- W272141240 cites W2047407620 @default.
- W272141240 cites W2049238083 @default.
- W272141240 cites W2050363122 @default.
- W272141240 cites W2053464278 @default.
- W272141240 cites W2056975727 @default.
- W272141240 cites W2062403124 @default.
- W272141240 cites W2067470163 @default.
- W272141240 cites W2069149078 @default.
- W272141240 cites W2072667894 @default.
- W272141240 cites W2076525549 @default.
- W272141240 cites W2077078281 @default.
- W272141240 cites W2081144622 @default.
- W272141240 cites W2101832146 @default.
- W272141240 cites W2107434784 @default.
- W272141240 cites W2127739372 @default.
- W272141240 cites W2128114904 @default.
- W272141240 cites W2132781048 @default.
- W272141240 cites W2136445888 @default.
- W272141240 cites W2143688649 @default.
- W272141240 cites W2147694941 @default.
- W272141240 cites W2152948116 @default.
- W272141240 cites W2162012775 @default.
- W272141240 cites W2164813423 @default.
- W272141240 cites W2165356074 @default.
- W272141240 cites W2172226435 @default.
- W272141240 cites W2172740242 @default.
- W272141240 cites W2263779592 @default.
- W272141240 cites W2322101615 @default.
- W272141240 cites W2328996377 @default.
- W272141240 cites W2501899318 @default.
- W272141240 cites W305801964 @default.
- W272141240 cites W4251267925 @default.
- W272141240 cites W4296265322 @default.
- W272141240 cites W60876240 @default.
- W272141240 doi "https://doi.org/10.1016/b978-0-12-800016-8.00006-4" @default.
- W272141240 hasPublicationYear "2015" @default.
- W272141240 type Work @default.
- W272141240 sameAs 272141240 @default.
- W272141240 citedByCount "11" @default.
- W272141240 countsByYear W2721412402015 @default.
- W272141240 countsByYear W2721412402016 @default.
- W272141240 countsByYear W2721412402018 @default.
- W272141240 countsByYear W2721412402019 @default.
- W272141240 countsByYear W2721412402020 @default.
- W272141240 countsByYear W2721412402021 @default.
- W272141240 countsByYear W2721412402022 @default.
- W272141240 countsByYear W2721412402023 @default.
- W272141240 crossrefType "book-chapter" @default.
- W272141240 hasAuthorship W272141240A5005444129 @default.
- W272141240 hasAuthorship W272141240A5018889796 @default.
- W272141240 hasAuthorship W272141240A5033996103 @default.
- W272141240 hasAuthorship W272141240A5036175961 @default.
- W272141240 hasAuthorship W272141240A5041307807 @default.
- W272141240 hasAuthorship W272141240A5041774544 @default.
- W272141240 hasConcept C118552586 @default.
- W272141240 hasConcept C1513209611 @default.
- W272141240 hasConcept C177713679 @default.
- W272141240 hasConcept C187212893 @default.
- W272141240 hasConcept C2426938 @default.
- W272141240 hasConcept C2781210498 @default.
- W272141240 hasConcept C2781433485 @default.
- W272141240 hasConcept C36434225 @default.
- W272141240 hasConcept C71924100 @default.
- W272141240 hasConcept C98274493 @default.
- W272141240 hasConceptScore W272141240C118552586 @default.
- W272141240 hasConceptScore W272141240C1513209611 @default.
- W272141240 hasConceptScore W272141240C177713679 @default.
- W272141240 hasConceptScore W272141240C187212893 @default.
- W272141240 hasConceptScore W272141240C2426938 @default.
- W272141240 hasConceptScore W272141240C2781210498 @default.
- W272141240 hasConceptScore W272141240C2781433485 @default.
- W272141240 hasConceptScore W272141240C36434225 @default.
- W272141240 hasConceptScore W272141240C71924100 @default.