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• W2724211025 endingPage "25028" @default.
• W2724211025 startingPage "25023" @default.
• W2724211025 abstract "Living cells exploit compartmentalization within organelles to spatially and temporally control reactions and pathways. Here, we use the all aqueous two phase system (ATPS) of poly(ethylene glycol) (PEG) and dextran to develop all water emulsion bodies, AWE-somes, a new class of encapsulated double emulsions as potential cell mimics. AWE-somes feature rigid polyelectrolyte (PE)/nanoparticle (NP) shells and double emulsion interiors. The shells form via complexation of PE and NP at interfaces of ATPS. The NPs, excluded from the drop phase, create an osmotic stress imbalance that removes water from the encapsulated phase and draws droplets of external PEG phase into the shells to form the double emulsion interior. We demonstrate that molecules can permeate the AWE-some shells, selectively partition into the internal droplets, and undergo reaction. AWE-somes have significant potential for creating functional, biocompatible protocell systems." @default.
• W2724211025 created "2017-07-14" @default.
• W2724211025 creator A5000139869 @default.
• W2724211025 creator A5078575240 @default.
• W2724211025 creator A5086030263 @default.
• W2724211025 date "2017-07-14" @default.
• W2724211025 modified "2023-10-18" @default.
• W2724211025 title "AWE-somes: All Water Emulsion Bodies with Permeable Shells and Selective Compartments" @default.
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• W2724211025 doi "https://doi.org/10.1021/acsami.7b05800" @default.
• W2724211025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28665113" @default.
• W2724211025 hasPublicationYear "2017" @default.
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