Matches in SemOpenAlex for { <https://semopenalex.org/work/W2724708448> ?p ?o ?g. }
- W2724708448 abstract "Neurodegenerative diseases often have a devastating impact on those affected. Retinal ganglion cell (RGC) loss is implicated in an array of diseases, including diabetic retinopathy and glaucoma, in addition to normal aging. Despite their importance, RGCs have been extremely difficult to study until now due in part to the fact that they comprise only a small percentage of the wide variety of cells in the retina. In addition, current isolation methods use intracellular markers to identify RGCs, which produce non-viable cells. These techniques also involve lengthy isolation protocols, so there is a lack of practical, standardized, and dependable methods to obtain and isolate RGCs. This work describes an efficient, comprehensive, and reliable method to isolate primary RGCs from mice retinae using a protocol based on both positive and negative selection criteria. The presented methods allow for the future study of RGCs, with the goal of better understanding the major decline in visual acuity that results from the loss of functional RGCs in neurodegenerative diseases." @default.
- W2724708448 created "2017-07-14" @default.
- W2724708448 creator A5003988583 @default.
- W2724708448 creator A5004822850 @default.
- W2724708448 creator A5009248333 @default.
- W2724708448 creator A5033891094 @default.
- W2724708448 creator A5034915579 @default.
- W2724708448 creator A5043519044 @default.
- W2724708448 creator A5064310124 @default.
- W2724708448 creator A5064629332 @default.
- W2724708448 date "2017-07-05" @default.
- W2724708448 modified "2023-09-23" @default.
- W2724708448 title "Isolation of Primary Murine Retinal Ganglion Cells (RGCs) by Flow Cytometry" @default.
- W2724708448 cites W1585637542 @default.
- W2724708448 cites W1770930219 @default.
- W2724708448 cites W184186015 @default.
- W2724708448 cites W1893444436 @default.
- W2724708448 cites W1968597772 @default.
- W2724708448 cites W1969830087 @default.
- W2724708448 cites W1973336785 @default.
- W2724708448 cites W1976688362 @default.
- W2724708448 cites W1985070835 @default.
- W2724708448 cites W1988092591 @default.
- W2724708448 cites W1992191441 @default.
- W2724708448 cites W2011220740 @default.
- W2724708448 cites W2013477456 @default.
- W2724708448 cites W2022868448 @default.
- W2724708448 cites W2024179689 @default.
- W2724708448 cites W2039127036 @default.
- W2724708448 cites W2044858838 @default.
- W2724708448 cites W2045733021 @default.
- W2724708448 cites W2050209237 @default.
- W2724708448 cites W2052789843 @default.
- W2724708448 cites W2059629742 @default.
- W2724708448 cites W2062808446 @default.
- W2724708448 cites W2065536861 @default.
- W2724708448 cites W2069758166 @default.
- W2724708448 cites W2073589440 @default.
- W2724708448 cites W2073762758 @default.
- W2724708448 cites W2079575303 @default.
- W2724708448 cites W2094884859 @default.
- W2724708448 cites W2099364812 @default.
- W2724708448 cites W2114570899 @default.
- W2724708448 cites W2124932841 @default.
- W2724708448 cites W2138422160 @default.
- W2724708448 cites W2143372471 @default.
- W2724708448 cites W2157892812 @default.
- W2724708448 cites W2168504128 @default.
- W2724708448 cites W2402954452 @default.
- W2724708448 cites W2411389072 @default.
- W2724708448 doi "https://doi.org/10.3791/55785" @default.
- W2724708448 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5608546" @default.
- W2724708448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28715391" @default.
- W2724708448 hasPublicationYear "2017" @default.
- W2724708448 type Work @default.
- W2724708448 sameAs 2724708448 @default.
- W2724708448 citedByCount "12" @default.
- W2724708448 countsByYear W27247084482018 @default.
- W2724708448 countsByYear W27247084482019 @default.
- W2724708448 countsByYear W27247084482020 @default.
- W2724708448 countsByYear W27247084482021 @default.
- W2724708448 countsByYear W27247084482022 @default.
- W2724708448 countsByYear W27247084482023 @default.
- W2724708448 crossrefType "journal-article" @default.
- W2724708448 hasAuthorship W2724708448A5003988583 @default.
- W2724708448 hasAuthorship W2724708448A5004822850 @default.
- W2724708448 hasAuthorship W2724708448A5009248333 @default.
- W2724708448 hasAuthorship W2724708448A5033891094 @default.
- W2724708448 hasAuthorship W2724708448A5034915579 @default.
- W2724708448 hasAuthorship W2724708448A5043519044 @default.
- W2724708448 hasAuthorship W2724708448A5064310124 @default.
- W2724708448 hasAuthorship W2724708448A5064629332 @default.
- W2724708448 hasBestOaLocation W27247084482 @default.
- W2724708448 hasConcept C134018914 @default.
- W2724708448 hasConcept C169760540 @default.
- W2724708448 hasConcept C2775941552 @default.
- W2724708448 hasConcept C2777093970 @default.
- W2724708448 hasConcept C2777624874 @default.
- W2724708448 hasConcept C2778527774 @default.
- W2724708448 hasConcept C2779829184 @default.
- W2724708448 hasConcept C2780827179 @default.
- W2724708448 hasConcept C55493867 @default.
- W2724708448 hasConcept C555293320 @default.
- W2724708448 hasConcept C60644358 @default.
- W2724708448 hasConcept C86803240 @default.
- W2724708448 hasConceptScore W2724708448C134018914 @default.
- W2724708448 hasConceptScore W2724708448C169760540 @default.
- W2724708448 hasConceptScore W2724708448C2775941552 @default.
- W2724708448 hasConceptScore W2724708448C2777093970 @default.
- W2724708448 hasConceptScore W2724708448C2777624874 @default.
- W2724708448 hasConceptScore W2724708448C2778527774 @default.
- W2724708448 hasConceptScore W2724708448C2779829184 @default.
- W2724708448 hasConceptScore W2724708448C2780827179 @default.
- W2724708448 hasConceptScore W2724708448C55493867 @default.
- W2724708448 hasConceptScore W2724708448C555293320 @default.
- W2724708448 hasConceptScore W2724708448C60644358 @default.
- W2724708448 hasConceptScore W2724708448C86803240 @default.
- W2724708448 hasIssue "125" @default.
- W2724708448 hasLocation W27247084481 @default.
- W2724708448 hasLocation W27247084482 @default.