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- W2725328587 abstract "Background and aims: A bidirectional relationship between type 2 diabetes(T2D) and depressive symptoms has been reported. The primaryaim was to analyze predictors of depressed mood in T2D. Secondly, theodds ratio of developing a clinically recognized depression in patientswith conspicuous screening result was evaluated.Materials and methods: 35,691 T2D patients aged ≥18 years (median[IQR]: 68.9 [59.2-76.5] years) from the German/Austrian multicenterprospective diabetes follow-up registry (DPV) were analyzed. All patientshad completed the WHO-5 questionnaire, a reliable and validated5-item screening tool for depression (score ≤7: likely depression). Logisticregression modeling (SAS 9.4) was applied to study potential predictors(e.g. demographics, regional aspect, diabetes therapy, glycemicS414 Diabetologia (2015) 58 (Suppl 1):S1–S607control) for depressed mood as well as the risk of developing clinicallyrecognized depression.Results: Depressed mood was present in 11.2% (n=4,000) of patientsscreened and thereby significantly more prevalent compared to the adultGerman population (DEGS study: 8.1%, p<0.001). Patients with likelydepression had a later diabetes onset (60.5 [49.6-70.2] vs. 58.3 [49.1-67.7] years, p<0.001) and were more often female (54.0 vs. 48.0%, p<0.001) compared to patients with inconspicuous results. Duration of diabetesdid not differ significantly between groups (7.6 [2.4-12.9] vs. 7.0[2.1-13.5] years, p=0.76). Young and very old age as well as female sexwere associated with depressed mood (table 1, model 1). Moreover, livingin northern federal states of Germany, poor glycemic control (HbA1c≥58 mmol/mol) and insulin treatment were significantly related to depressedmood in T2D (table 1). Overall, the odds of developing a clinicaldiagnosis of depression was 1.95 (95%CI: 1.66-2.29) times higher inpatients scored ≤7 in the WHO-5 questionnaire.Conclusion: Depressed mood is a frequent psychological comorbidity inadult T2D patients. In clinical care, routinely screening for psychologicalproblems as recommended by guidelines is absolutely advisable, especiallyin high-risk patients." @default.
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- W2725328587 date "2015-01-01" @default.
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- W2725328587 title "Female sex, young and old age, northern German residency, high HbA1c and insulin use predict depressed mood in 35,691 T2D patients" @default.
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