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- W2725552020 abstract "Little is known about venom in young developmental stages of animals. The appearance of toxins and stinging cells during early embryonic stages in the sea anemone Nematostella vectensis suggests that venom is already expressed in eggs and larvae of this species. Here, we harness transcriptomic, biochemical and transgenic tools to study venom production dynamics in Nematostella. We find that venom composition and arsenal of toxin-producing cells change dramatically between developmental stages of this species. These findings can be explained by the vastly different interspecific interactions of each life stage, as individuals develop from a miniature non-feeding mobile planula to a larger sessile polyp that predates on other animals and interact differently with predators. Indeed, behavioral assays involving prey, predators and Nematostella are consistent with this hypothesis. Further, the results of this work suggest a much wider and dynamic venom landscape than initially appreciated in animals with a complex life cycle." @default.
- W2725552020 created "2017-07-14" @default.
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- W2725552020 date "2018-02-09" @default.
- W2725552020 modified "2023-10-01" @default.
- W2725552020 title "Dynamics of venom composition across a complex life cycle" @default.
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- W2725552020 doi "https://doi.org/10.7554/elife.35014" @default.
- W2725552020 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5832418" @default.
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