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- W2725644489 abstract "AbstractThe aim of this study was to develop a potential novel formulation of carbopol-based nanoemulsion gel containing apigenin using tamarind gum emulsifier which was having the smallest droplet size, the highest drug content, and a good physical stability for Skin delivery. Apigenin loaded nanoemulsion was prepared by high speed homogenization method and they were characterized with respect to morphology, zeta potential, differential scanning calorimeter study, and penetration studies. In-vitro release studies and skin permeation of apigenin loaded nanoemulsion by goat abdominal skin was determined using Franz diffusion cell and confocal laser scanning microscope (CLSM). The cytotoxicity of the reported formulation was evaluated in HaCaT Cells (A) and A431 cells (B) by MTT assay. The nanoemulsion formulation showed droplet size, polydispersity index, and zeta potential of 183.31 nm, 0.532, and 31.9 mV, respectively. The nanoemulsions were characterized by TEM demonstrated spherical droplets and FTIR t..." @default.
- W2725644489 created "2017-07-14" @default.
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- W2725644489 date "2017-01-01" @default.
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- W2725644489 title "Fabrication, <i>in-vitro</i> characterization, and enhanced <i>in-vivo</i> evaluation of carbopol-based nanoemulsion gel of apigenin for UV-induced skin carcinoma" @default.
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- W2725644489 doi "https://doi.org/10.1080/10717544.2017.1344333" @default.
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