Matches in SemOpenAlex for { <https://semopenalex.org/work/W2725816324> ?p ?o ?g. }
- W2725816324 endingPage "975" @default.
- W2725816324 startingPage "969" @default.
- W2725816324 abstract "Chlorogenic acid (CGA) is a quinic acid conjugate of caffeic acid, and a phytochemical found in many fruits and beverages that acts as an antioxidant. The present study investigated the effects of CGA supplementation during in vitro maturation (IVM), on in vitro development of porcine oocytes, to improve the porcine in vitro production (IVP) system. Oocytes were matured either without (control) or with CGA (10, 50, 100 and 200 μM). Subsequently, the matured oocytes were fertilized and cultured in vitro for 7 day. The rates of maturation, fertilization and blastocyst formation of oocytes matured with 50 μM CGA were significantly (p < .05) higher than those of the control oocytes. Hydrogen peroxide (H2O2) is one of the reactive oxygen species and induces DNA damage in porcine oocytes. When oocytes were matured with 1 mM H2O2 to assess the protective effect of CGA, 50 μM CGA supplementation improved the maturation rate and the proportion of DNA-fragmented nuclei in oocytes compared with control oocytes matured without CGA. Moreover, when oocytes were matured with either 50 μM CGA (control) or caffeic acid (10, 50 and 100 μM), the rates of maturation, fertilization and the blastocyst formation of oocytes matured with 50 μM CGA were similar to those of oocytes matured with 10 and 50 μM caffeic acid. Our results suggest that CGA has comparable effects to caffeic acid, and IVM with 50 μM CGA is particularly beneficial to IVP of porcine embryos and protects oocytes from DNA damage induced by oxidative stress. Supplementation of CGA to the maturation medium has a potential to improve porcine IVP system." @default.
- W2725816324 created "2017-07-14" @default.
- W2725816324 creator A5004952269 @default.
- W2725816324 creator A5007605346 @default.
- W2725816324 creator A5051573825 @default.
- W2725816324 creator A5053502532 @default.
- W2725816324 creator A5058038560 @default.
- W2725816324 creator A5066921194 @default.
- W2725816324 creator A5076409992 @default.
- W2725816324 creator A5083635582 @default.
- W2725816324 date "2017-06-28" @default.
- W2725816324 modified "2023-10-03" @default.
- W2725816324 title "Chlorogenic acid supplementation during in vitro maturation improves maturation, fertilization and developmental competence of porcine oocytes" @default.
- W2725816324 cites W1921234578 @default.
- W2725816324 cites W1926252608 @default.
- W2725816324 cites W1946012906 @default.
- W2725816324 cites W1967923229 @default.
- W2725816324 cites W1969713193 @default.
- W2725816324 cites W1975247891 @default.
- W2725816324 cites W1979445185 @default.
- W2725816324 cites W1987793536 @default.
- W2725816324 cites W1991039537 @default.
- W2725816324 cites W1993071134 @default.
- W2725816324 cites W2008905107 @default.
- W2725816324 cites W2012563490 @default.
- W2725816324 cites W2018438226 @default.
- W2725816324 cites W2023208657 @default.
- W2725816324 cites W2026336054 @default.
- W2725816324 cites W2046160648 @default.
- W2725816324 cites W2049260203 @default.
- W2725816324 cites W2053593695 @default.
- W2725816324 cites W2058940985 @default.
- W2725816324 cites W2060371040 @default.
- W2725816324 cites W2065082156 @default.
- W2725816324 cites W2070030461 @default.
- W2725816324 cites W2070386417 @default.
- W2725816324 cites W2070677094 @default.
- W2725816324 cites W2074017674 @default.
- W2725816324 cites W2076294894 @default.
- W2725816324 cites W2077927412 @default.
- W2725816324 cites W2081151075 @default.
- W2725816324 cites W2086959952 @default.
- W2725816324 cites W2090808291 @default.
- W2725816324 cites W2093826154 @default.
- W2725816324 cites W2099468754 @default.
- W2725816324 cites W2104551906 @default.
- W2725816324 cites W2105928417 @default.
- W2725816324 cites W2116574982 @default.
- W2725816324 cites W2122487724 @default.
- W2725816324 cites W2124369979 @default.
- W2725816324 cites W2125726311 @default.
- W2725816324 cites W2156701434 @default.
- W2725816324 cites W2165796896 @default.
- W2725816324 cites W2167939240 @default.
- W2725816324 cites W2168139864 @default.
- W2725816324 cites W2168439614 @default.
- W2725816324 cites W2168801847 @default.
- W2725816324 cites W2170033315 @default.
- W2725816324 cites W2263512472 @default.
- W2725816324 doi "https://doi.org/10.1111/rda.13005" @default.
- W2725816324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28660662" @default.
- W2725816324 hasPublicationYear "2017" @default.
- W2725816324 type Work @default.
- W2725816324 sameAs 2725816324 @default.
- W2725816324 citedByCount "42" @default.
- W2725816324 countsByYear W27258163242018 @default.
- W2725816324 countsByYear W27258163242019 @default.
- W2725816324 countsByYear W27258163242020 @default.
- W2725816324 countsByYear W27258163242021 @default.
- W2725816324 countsByYear W27258163242022 @default.
- W2725816324 countsByYear W27258163242023 @default.
- W2725816324 crossrefType "journal-article" @default.
- W2725816324 hasAuthorship W2725816324A5004952269 @default.
- W2725816324 hasAuthorship W2725816324A5007605346 @default.
- W2725816324 hasAuthorship W2725816324A5051573825 @default.
- W2725816324 hasAuthorship W2725816324A5053502532 @default.
- W2725816324 hasAuthorship W2725816324A5058038560 @default.
- W2725816324 hasAuthorship W2725816324A5066921194 @default.
- W2725816324 hasAuthorship W2725816324A5076409992 @default.
- W2725816324 hasAuthorship W2725816324A5083635582 @default.
- W2725816324 hasConcept C105702510 @default.
- W2725816324 hasConcept C16685009 @default.
- W2725816324 hasConcept C185592680 @default.
- W2725816324 hasConcept C196843134 @default.
- W2725816324 hasConcept C2775966511 @default.
- W2725816324 hasConcept C2778004101 @default.
- W2725816324 hasConcept C2778177303 @default.
- W2725816324 hasConcept C2778224086 @default.
- W2725816324 hasConcept C2780117898 @default.
- W2725816324 hasConcept C55493867 @default.
- W2725816324 hasConcept C59822182 @default.
- W2725816324 hasConcept C71924100 @default.
- W2725816324 hasConcept C86803240 @default.
- W2725816324 hasConcept C87073359 @default.
- W2725816324 hasConcept C88972607 @default.
- W2725816324 hasConcept C95444343 @default.
- W2725816324 hasConceptScore W2725816324C105702510 @default.
- W2725816324 hasConceptScore W2725816324C16685009 @default.