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- W2726045052 abstract "Toll-like receptors (TLRs) play a crucial role in innate immunity by recognizing specific pathogen-associated molecular patterns, including lipoproteins, lipopeptides, lipopolysaccharide, flagellin, dsRNA, ssRNA and CpG DNA motifs. Although significant effects of TLRs on immunity have been reported in most vertebrates and some invertebrates, the complete TLR superfamily has not been systematically characterized in scallops. In this study, 18 TLR genes were identified from Yesso scallop (Patinopecten yessoensis) using whole-genome scanning. Phylogenetic and protein structural analyses were performed to determine the identities and evolutionary relationships of the 18 genes. Extensive expansion of TLR genes from the Yesso scallop genome indicated gene duplication events. In addition, expression profiling of PyTLRs was performed at different acidifying exposure levels (pH = 6.50, 7.50) with different challenge durations (3, 6, 12 and 24 h) via in silico analysis using transcriptome and genome databases. Our results confirmed the inducible expression patterns of PyTLRs under acidifying exposure, and the responses to immune stress may have arisen through adaptive recruitment of tandem duplications of TLR genes. Collectively, this study provides novel insight into PyTLRs as well as the specific role and response of TLR signaling pathways in host immune responses against acidifying exposure in bivalves." @default.
- W2726045052 created "2017-07-14" @default.
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- W2726045052 date "2017-09-01" @default.
- W2726045052 modified "2023-10-14" @default.
- W2726045052 title "Genome-wide identification, characterization and expression analyses of TLRs in Yesso scallop (Patinopecten yessoensis) provide insight into the disparity of responses to acidifying exposure in bivalves" @default.
- W2726045052 cites W114561417 @default.
- W2726045052 cites W1522842079 @default.
- W2726045052 cites W1603858169 @default.
- W2726045052 cites W1881000532 @default.
- W2726045052 cites W1971010512 @default.
- W2726045052 cites W1971231926 @default.
- W2726045052 cites W1978926805 @default.
- W2726045052 cites W1978953057 @default.
- W2726045052 cites W1980855342 @default.
- W2726045052 cites W1981014132 @default.
- W2726045052 cites W1982637996 @default.
- W2726045052 cites W1987338938 @default.
- W2726045052 cites W1988314455 @default.
- W2726045052 cites W1988376786 @default.
- W2726045052 cites W1994060026 @default.
- W2726045052 cites W1995744610 @default.
- W2726045052 cites W1995877471 @default.
- W2726045052 cites W2002225831 @default.
- W2726045052 cites W2004465286 @default.
- W2726045052 cites W2005452204 @default.
- W2726045052 cites W2011593091 @default.
- W2726045052 cites W2013309257 @default.
- W2726045052 cites W2013920147 @default.
- W2726045052 cites W2024172842 @default.
- W2726045052 cites W2026432913 @default.
- W2726045052 cites W2027965015 @default.
- W2726045052 cites W2029723989 @default.
- W2726045052 cites W2029851565 @default.
- W2726045052 cites W2044992198 @default.
- W2726045052 cites W2048830824 @default.
- W2726045052 cites W2059805279 @default.
- W2726045052 cites W2071627706 @default.
- W2726045052 cites W2073523429 @default.
- W2726045052 cites W2074964253 @default.
- W2726045052 cites W2075787303 @default.
- W2726045052 cites W2078395832 @default.
- W2726045052 cites W2081171444 @default.
- W2726045052 cites W2099669431 @default.
- W2726045052 cites W2109491705 @default.
- W2726045052 cites W2112092792 @default.
- W2726045052 cites W2113297575 @default.
- W2726045052 cites W2115185894 @default.
- W2726045052 cites W2119129458 @default.
- W2726045052 cites W2126743345 @default.
- W2726045052 cites W2127517102 @default.
- W2726045052 cites W2129662167 @default.
- W2726045052 cites W2132087745 @default.
- W2726045052 cites W2132120234 @default.
- W2726045052 cites W2133449490 @default.
- W2726045052 cites W2135362707 @default.
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- W2726045052 cites W2137015675 @default.
- W2726045052 cites W2137590150 @default.
- W2726045052 cites W2152207030 @default.
- W2726045052 cites W2152399502 @default.
- W2726045052 cites W2154403718 @default.
- W2726045052 cites W2155711945 @default.
- W2726045052 cites W2156517152 @default.
- W2726045052 cites W2159743369 @default.
- W2726045052 cites W2162365320 @default.
- W2726045052 cites W2167438636 @default.
- W2726045052 cites W2170254955 @default.
- W2726045052 cites W2173001546 @default.
- W2726045052 cites W2181278798 @default.
- W2726045052 cites W2201853374 @default.
- W2726045052 cites W2264133913 @default.
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- W2726045052 cites W2416004170 @default.
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- W2726045052 cites W568355506 @default.
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- W2726045052 doi "https://doi.org/10.1016/j.fsi.2017.07.020" @default.
- W2726045052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28698128" @default.
- W2726045052 hasPublicationYear "2017" @default.
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