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• W2726396965 abstract "Objective: The objective of this paper was to link the phytochemical and metabolic research treating quinolinic acid induced oxidative stress in neurodegenerative disorders.Methods: Quinolinic acid, a metabolite of the kynurenine pathway of tryptophan catabolism, plays a role in the oxidative stress associated with many neurological disorders and is used to simulate disorders such as Parkinson’s disease.Results: In these models, phytochemicals have been shown to reduce striatal lesion size, reduce inflammation and prevent lipid peroxidation caused by quinolinic acid.Conclusion: These results suggest that phenolic compounds, a class of phytochemicals, including flavonoids and diarylheptanoids, should be further studied to develop new treatments for oxidative stress related neurological disorders." @default.
• W2726396965 created "2017-07-14" @default.
• W2726396965 creator A5069407542 @default.
• W2726396965 date "2017-06-26" @default.
• W2726396965 modified "2023-10-03" @default.
• W2726396965 title "Phytochemical treatments target kynurenine pathway induced oxidative stress" @default.
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• W2726396965 doi "https://doi.org/10.1080/13510002.2017.1343223" @default.
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