FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2726487217> ?p ?o ?g. }

• W2726487217 endingPage "141" @default.
• W2726487217 startingPage "134" @default.
• W2726487217 abstract "In vitro reporter gene assays detecting dioxin-like compounds have been developed and validated since the middle 1990's, and applied to the determination of dioxin-like activities in various samples for their risk management. Data on characterizing the potency of individual brominated dioxins and their activity in mixture with chlorinated dioxins are still limited on the cell-based assay. This study characterized the dioxin-like activities of the 32 brominated dioxins, such as polybrominated dibenzo-p-dioxins, polybrominated dibenzofurans (PBDFs), coplanar polybrominated biphenyls, mixed halogenated dibenzo-p-dioxins and dibenzofurans (PXDFs), as a sole component or in a mixture by DR-CALUX (dioxin-responsive chemically activated luciferase expression) using the rat hepatoma H4IIE cell line and XDS-CALUX (xenobiotic detection systems–chemically activated luciferase expression) assays using the mouse hepatoma H1L6.1 cell line. The 2,3,7,8-TCDD-relative potencies (REPs) of most of the brominated dioxins were within a factor of 10 of the WHO toxicity equivalency factor (WHO-TEF) for the chlorinated analogues. The REPs of a few PXDFs were an order of magnitude higher than the corresponding WHO-TEFs, indicating their toxicological importance. Results with reconstituted mixtures suggest that the activity of brominated and chlorinated dioxins in both CALUX assays was dose-additive. Thus, obtained results indicated the applicability of the CALUX assays as screening tools of brominated dioxins together with their chlorinated analogues." @default.
• W2726487217 created "2017-07-14" @default.
• W2726487217 creator A5034882455 @default.
• W2726487217 creator A5036438728 @default.
• W2726487217 creator A5040132572 @default.
• W2726487217 creator A5055703781 @default.
• W2726487217 creator A5072123710 @default.
• W2726487217 creator A5091389392 @default.
• W2726487217 date "2017-10-01" @default.
• W2726487217 modified "2023-10-16" @default.
• W2726487217 title "Dioxin-like activity of brominated dioxins as individual compounds or mixtures in in vitro reporter gene assays with rat and mouse hepatoma cell lines" @default.
• W2726487217 cites W1968821452 @default.
• W2726487217 cites W1977017738 @default.
• W2726487217 cites W1987304592 @default.
• W2726487217 cites W1991461734 @default.
• W2726487217 cites W1997797704 @default.
• W2726487217 cites W2011582760 @default.
• W2726487217 cites W2013025233 @default.
• W2726487217 cites W2041088900 @default.
• W2726487217 cites W2044331883 @default.
• W2726487217 cites W2075554243 @default.
• W2726487217 cites W2080330359 @default.
• W2726487217 cites W2098123343 @default.
• W2726487217 cites W2100180451 @default.
• W2726487217 cites W2108970858 @default.
• W2726487217 cites W2113750680 @default.
• W2726487217 cites W2118382882 @default.
• W2726487217 cites W2129648214 @default.
• W2726487217 cites W2148132810 @default.
• W2726487217 cites W2159312550 @default.
• W2726487217 cites W2166546592 @default.
• W2726487217 cites W2212212986 @default.
• W2726487217 cites W2339775772 @default.
• W2726487217 doi "https://doi.org/10.1016/j.tiv.2017.06.025" @default.
• W2726487217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28669845" @default.
• W2726487217 hasPublicationYear "2017" @default.
• W2726487217 type Work @default.
• W2726487217 sameAs 2726487217 @default.
• W2726487217 citedByCount "15" @default.
• W2726487217 countsByYear W27264872172019 @default.
• W2726487217 countsByYear W27264872172020 @default.
• W2726487217 countsByYear W27264872172021 @default.
• W2726487217 countsByYear W27264872172022 @default.
• W2726487217 countsByYear W27264872172023 @default.
• W2726487217 crossrefType "journal-article" @default.
• W2726487217 hasAuthorship W2726487217A5034882455 @default.
• W2726487217 hasAuthorship W2726487217A5036438728 @default.
• W2726487217 hasAuthorship W2726487217A5040132572 @default.
• W2726487217 hasAuthorship W2726487217A5055703781 @default.
• W2726487217 hasAuthorship W2726487217A5072123710 @default.
• W2726487217 hasAuthorship W2726487217A5091389392 @default.
• W2726487217 hasConcept C104317684 @default.
• W2726487217 hasConcept C104488531 @default.
• W2726487217 hasConcept C107872376 @default.
• W2726487217 hasConcept C114246631 @default.
• W2726487217 hasConcept C150194340 @default.
• W2726487217 hasConcept C161733203 @default.
• W2726487217 hasConcept C178790620 @default.
• W2726487217 hasConcept C185592680 @default.
• W2726487217 hasConcept C202751555 @default.
• W2726487217 hasConcept C2776044436 @default.
• W2726487217 hasConcept C2778209978 @default.
• W2726487217 hasConcept C2779732650 @default.
• W2726487217 hasConcept C2780990795 @default.
• W2726487217 hasConcept C2908926047 @default.
• W2726487217 hasConcept C29730261 @default.
• W2726487217 hasConcept C33618052 @default.
• W2726487217 hasConcept C54355233 @default.
• W2726487217 hasConcept C55493867 @default.
• W2726487217 hasConcept C81885089 @default.
• W2726487217 hasConcept C82685317 @default.
• W2726487217 hasConcept C86803240 @default.
• W2726487217 hasConceptScore W2726487217C104317684 @default.
• W2726487217 hasConceptScore W2726487217C104488531 @default.
• W2726487217 hasConceptScore W2726487217C107872376 @default.
• W2726487217 hasConceptScore W2726487217C114246631 @default.
• W2726487217 hasConceptScore W2726487217C150194340 @default.
• W2726487217 hasConceptScore W2726487217C161733203 @default.
• W2726487217 hasConceptScore W2726487217C178790620 @default.
• W2726487217 hasConceptScore W2726487217C185592680 @default.
• W2726487217 hasConceptScore W2726487217C202751555 @default.
• W2726487217 hasConceptScore W2726487217C2776044436 @default.
• W2726487217 hasConceptScore W2726487217C2778209978 @default.
• W2726487217 hasConceptScore W2726487217C2779732650 @default.
• W2726487217 hasConceptScore W2726487217C2780990795 @default.
• W2726487217 hasConceptScore W2726487217C2908926047 @default.
• W2726487217 hasConceptScore W2726487217C29730261 @default.
• W2726487217 hasConceptScore W2726487217C33618052 @default.
• W2726487217 hasConceptScore W2726487217C54355233 @default.
• W2726487217 hasConceptScore W2726487217C55493867 @default.
• W2726487217 hasConceptScore W2726487217C81885089 @default.
• W2726487217 hasConceptScore W2726487217C82685317 @default.
• W2726487217 hasConceptScore W2726487217C86803240 @default.
• W2726487217 hasFunder F4320323648 @default.
• W2726487217 hasLocation W27264872171 @default.
• W2726487217 hasLocation W27264872172 @default.
• W2726487217 hasOpenAccess W2726487217 @default.
• W2726487217 hasPrimaryLocation W27264872171 @default.

• next