FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2728010908> ?p ?o ?g. }

• W2728010908 endingPage "171" @default.
• W2728010908 startingPage "153" @default.
• W2728010908 abstract "Cancer theranostic is an approach that combines cancer diagnostic and therapeutic capabilities into a single agent. We synthesized Gadolinium-doped mesoporous TiO2 microbeads (TiO2 + xGd MBs; x = 0%, 5%, and 10%), which can be used as a contrast agent in magnetic resonance imaging and as a photosensitizer in photodynamic therapy. Human osteosarcoma MG-63 cells were used as an in vitro model for cancer cells. In preliminary experiments, we studied the cytotoxicity of TiO2 + xGd MBs with different Gd contents (0%, 5%, and 10%). To study cellular internalization of different TiO2 + xGd MBs, differential interference microscopy and transmission electron microscopy were performed. Phototoxicity of Gd-doped TiO2 MBs (TiO2 + 5%Gd and TiO2 + 10%Gd MBs) was evaluated and compared with undoped TiO2 MBs to determine if Gd-doping can be used to design TiO2 MBs for theranostic medicinal purposes. The viability of MG-63 cells exposed to TiO2 + xGd MBs and UV-A radiation was examined by resazurin assay, neutral red uptake assay, and differential staining using propidium iodide and Hoechst 33342. All the tested TiO2 + xGd MBs were internalized by MG-63 cells and significantly reduced cell viability after 3 min UV-A radiation, while the viability of untreated cells was unaffected by 3 min radiation. Moreover, our results show that MG-63 cells internalize TiO2 + 5%Gd MBs and TiO2 + 10%Gd MBs to a much greater extent than undoped TiO2 MBs, which resulted in higher phototoxicity of Gd-doped TiO2 MBs. These outcomes suggest that Gd-doped TiO2 MBs have a potential use in theranostic medicine." @default.
• W2728010908 created "2017-07-14" @default.
• W2728010908 creator A5016408999 @default.
• W2728010908 creator A5025582821 @default.
• W2728010908 creator A5048217980 @default.
• W2728010908 creator A5059852860 @default.
• W2728010908 creator A5068033079 @default.
• W2728010908 creator A5071309662 @default.
• W2728010908 creator A5087250445 @default.
• W2728010908 creator A5087927274 @default.
• W2728010908 date "2017-01-01" @default.
• W2728010908 modified "2023-09-29" @default.
• W2728010908 title "Phototoxicity of Mesoporous TiO 2 + Gd Microbeads With Theranostic Potential" @default.
• W2728010908 cites W1596848781 @default.
• W2728010908 cites W1754660988 @default.
• W2728010908 cites W1964066906 @default.
• W2728010908 cites W1968029051 @default.
• W2728010908 cites W1968376888 @default.
• W2728010908 cites W1969795902 @default.
• W2728010908 cites W1972721832 @default.
• W2728010908 cites W1979284608 @default.
• W2728010908 cites W1987337379 @default.
• W2728010908 cites W2002528172 @default.
• W2728010908 cites W2006314420 @default.
• W2728010908 cites W2007446526 @default.
• W2728010908 cites W2013292515 @default.
• W2728010908 cites W2028989051 @default.
• W2728010908 cites W2030176647 @default.
• W2728010908 cites W2034717709 @default.
• W2728010908 cites W2040914101 @default.
• W2728010908 cites W2042249858 @default.
• W2728010908 cites W2054420074 @default.
• W2728010908 cites W2054917280 @default.
• W2728010908 cites W2065857667 @default.
• W2728010908 cites W2068920186 @default.
• W2728010908 cites W2069376894 @default.
• W2728010908 cites W2082902103 @default.
• W2728010908 cites W2094005944 @default.
• W2728010908 cites W2099342434 @default.
• W2728010908 cites W2101471556 @default.
• W2728010908 cites W2109803081 @default.
• W2728010908 cites W2114131935 @default.
• W2728010908 cites W2116085637 @default.
• W2728010908 cites W2130386496 @default.
• W2728010908 cites W2138405719 @default.
• W2728010908 cites W2149200950 @default.
• W2728010908 cites W2152515195 @default.
• W2728010908 cites W2156795782 @default.
• W2728010908 cites W2166013785 @default.
• W2728010908 cites W2169044052 @default.
• W2728010908 cites W2170112386 @default.
• W2728010908 cites W2195373690 @default.
• W2728010908 cites W2235523093 @default.
• W2728010908 cites W2255462078 @default.
• W2728010908 cites W2320574135 @default.
• W2728010908 cites W2334327693 @default.
• W2728010908 cites W2473103604 @default.
• W2728010908 cites W2485195807 @default.
• W2728010908 cites W2580860671 @default.
• W2728010908 cites W2605043249 @default.
• W2728010908 cites W2606901501 @default.
• W2728010908 doi "https://doi.org/10.1016/bs.abl.2017.06.002" @default.
• W2728010908 hasPublicationYear "2017" @default.
• W2728010908 type Work @default.
• W2728010908 sameAs 2728010908 @default.
• W2728010908 citedByCount "4" @default.
• W2728010908 countsByYear W27280109082019 @default.
• W2728010908 countsByYear W27280109082022 @default.
• W2728010908 crossrefType "book-chapter" @default.
• W2728010908 hasAuthorship W2728010908A5016408999 @default.
• W2728010908 hasAuthorship W2728010908A5025582821 @default.
• W2728010908 hasAuthorship W2728010908A5048217980 @default.
• W2728010908 hasAuthorship W2728010908A5059852860 @default.
• W2728010908 hasAuthorship W2728010908A5068033079 @default.
• W2728010908 hasAuthorship W2728010908A5071309662 @default.
• W2728010908 hasAuthorship W2728010908A5087250445 @default.
• W2728010908 hasAuthorship W2728010908A5087927274 @default.
• W2728010908 hasConcept C109316439 @default.
• W2728010908 hasConcept C121608353 @default.
• W2728010908 hasConcept C12554922 @default.
• W2728010908 hasConcept C126322002 @default.
• W2728010908 hasConcept C13965031 @default.
• W2728010908 hasConcept C171250308 @default.
• W2728010908 hasConcept C178790620 @default.
• W2728010908 hasConcept C185592680 @default.
• W2728010908 hasConcept C190283241 @default.
• W2728010908 hasConcept C192562407 @default.
• W2728010908 hasConcept C202751555 @default.
• W2728010908 hasConcept C20639190 @default.
• W2728010908 hasConcept C2775934118 @default.
• W2728010908 hasConcept C2781469039 @default.
• W2728010908 hasConcept C31573885 @default.
• W2728010908 hasConcept C53227056 @default.
• W2728010908 hasConcept C55493867 @default.
• W2728010908 hasConcept C557651011 @default.
• W2728010908 hasConcept C71924100 @default.
• W2728010908 hasConcept C75473681 @default.
• W2728010908 hasConcept C86803240 @default.

• next