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• W2728532034 abstract "AbstractThe effectiveness of an upfront combination therapy of pulmonary arterial vasodilators on pulmonary arterial hypertension (PAH) associated with systemic lupus erythematosus (SLE) has not yet been established. Here we present two cases of SLE-PAH successfully treated by such a regimen. Case 1 was a 42-year-old Chinese female who was diagnosed as SLE based on 1997 American College of Rheumatology (ACR) criteria for arthritis, lymphocytopenia, thrombocytopenia, and positivity for anti-nuclear antibody (ANA) and anti-DNA antibody (ADNA). PAH was diagnosed simultaneously based on increased mean pulmonary arterial pressure (mPAP) (44mmHg) in right heart catheterisation. She was treated with macitentan, tadalaphil, and beraprost sodium, as an upfront triple combination therapy in addition to 45mg/day of prednisolone (PSL). She was successfully treated, resulting in a decrease of right ventricular systolic pressure (RVSP) on echocardiography from 68.4mmHg to 31.4mmHg within 4 months. Case 2 was a 34-year-..." @default.
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• W2728532034 date "2017-01-31" @default.
• W2728532034 modified "2023-09-27" @default.
• W2728532034 title "The effectiveness of upfront pulmonary vasodilators combination therapy in addition to corticosteroids for pulmonary arterial hypertension associated with systemic lupus erythematosus: two successful cases utilising both corticosteroids and an upfront combination of vasodilators" @default.
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• W2728532034 doi "https://doi.org/10.1080/24725625.2016.1277457" @default.
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