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- W2729007937 abstract "Williams et al. (Nat. Genet. 48:238-224, 2016) recently reported neutral tumor evolution in one third of 904 samples from The Cancer Genome Atlas. Here, we assess the reproducibility and validity of their method and the extent of positive selection in subclonal mutations across cancer types. Our results do not support observable neutral tumor evolution and uncover strong positive selection within subclonal mutations across cancers." @default.
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- W2729007937 date "2017-06-30" @default.
- W2729007937 modified "2023-10-17" @default.
- W2729007937 title "Neutral tumor evolution?" @default.
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- W2729007937 doi "https://doi.org/10.1101/158006" @default.
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