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- W2729041943 abstract "Sigma-1 receptor radioligands have the potential to detect and monitor various neurological diseases. Because sigma-1 receptors are believed to be associated withnumerous psychiatric conditions and neurodegenerative diseases, radioligands for sigma-1 receptors have the potential to serve as novel diagnostic tools and may be useful in assessing treatment effectiveness. A benzothiazolone 18F-labeled sigma-1 receptor ligand,CM304, has demonstrated promise as a specific positron emission tomography radiotracer for visualizing sigma-1 receptors in living subjects. Based on CM304, backupmolecules were created to improve the overall drug profile, including half- life and bioavailability." @default.
- W2729041943 created "2017-07-14" @default.
- W2729041943 creator A5067982630 @default.
- W2729041943 date "2015-05-01" @default.
- W2729041943 modified "2023-09-27" @default.
- W2729041943 title "Design and Synthesis of Sigma-1 Probe for Positron Emission Tomography (PET) Imaging" @default.
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