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- W2729129655 abstract "Abstract Aim This study aimed to assess the efficacy of the endometrial receptivity array ( ERA ) as a diagnostic tool and the impact of personalized embryo transfer ( pET ) for the treatment of patients with recurrent implantation failure ( RIF ) in Japan. Methods Fifty patients with a history of RIF with frozen‐thawed blastocyst transfers were recruited from July, 2015 to April, 2016. Endometrial sampling for the ERA and histological dating and a pET according to the ERA were performed. The receptive (R) or non‐receptive ( NR ) status of the endometrium as a result of the first ERA , endometrial dating, and pregnancy rates after the pET were analyzed. Results Of the patients with RIF , 12 (24%) were NR . Among them, eight (66.7%) were prereceptive. A clinical follow‐up was possible in 44 patients who underwent the pET . The pregnancy rates were 58.8% per patient and 35.3% per first pET in the R patients and 50.0% per patient and 50.0% per first pET in the NR patients. Discrepancies between the ERA results and histological dating were seen more in the NR patients than in the R patients. Conclusions For patients with unexplained RIF , there is a significance in searching for their personal window of implantation ( WOI ) using the ERA , considering the percentage of those who were NR and the pregnancy rates that resulted from the pET . By transferring euploid embryos in a personal WOI , much better pregnancy rates are expected." @default.
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- W2729129655 date "2017-06-27" @default.
- W2729129655 modified "2023-10-03" @default.
- W2729129655 title "Efficacy of the endometrial receptivity array for repeated implantation failure in Japan: A retrospective, two-centers study" @default.
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- W2729129655 doi "https://doi.org/10.1002/rmb2.12041" @default.
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