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- W272937970 abstract "Objective. To determine tolerability and effectiveness of continuous vagus nerve stimulation (VNS) in patients with drug resistance epilepsy (DRE). Patients and Methods. A VNS system was implanted to 9 adults (aged 14–38) with DRE. The duration of catamnesis was 8–12 months. Results. During the first 2–3 months after the VNS system had been implanted, seizure frequency reduced by over 50% in half of the patients with DRE. The remaining patients showed a similar positive effect 8–12 months after the VNS parameters had been adjusted. A decrease in seizure frequency, duration and severity, as well as shortening of the post-seizure period were observed in 12.5% of patients. Negative side effects, such as dysphonia and throat discomfort, were found in 12.5% of patients. These undesirable effects were eliminated by adjusting magnetic stim- ulation parameters. Significant positive EEG dynamics, such as regression of paroxysmal epileptic activity, were obtained in 62.5% the cases. Conclusions. VNS therapy is a safe and effective treatment method for reducing the frequency and severity of seizures in patients with DRE." @default.
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- W272937970 date "2014-07-09" @default.
- W272937970 modified "2023-10-06" @default.
- W272937970 title "Experience of Using Vagus Nerve Stimulation to Treat Drug Resistant Epilepsy" @default.
- W272937970 doi "https://doi.org/10.14412/2074-2711-2014-1s-18-21" @default.
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