FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2729381590> ?p ?o ?g. }

• W2729381590 endingPage "176" @default.
• W2729381590 startingPage "176" @default.
• W2729381590 abstract "Background/Aims: Hepatitis D virus (HDV) is a defective RNA virus that is dependent on hepatitis B surface antigen (HBsAg) for transmission and replication. HDV significance arises from the possibility of poor prognosis of hepatitis B virus (HBV) infection. In Saudi Arabia, HDV prevalence varied from 8 to 32% before the HBV vaccination program and ranged from 0 to 14.7% after the vaccination program was started. The last study, performed in 2004, showed a prevalence of 8.6% in hospital-based HBV cases and 3.3% in healthy donors. The aim of this study was to investigate the prevalence and molecular characterization of HDV in chronic hepatitis B (CHB) patients at the King Abdulaziz University Hospital in Jeddah, Saudi Arabia by molecular and serological techniques. To the best of our knowledge, this is the first study to detect HDV at the molecular level in Saudi Arabia. Patients and Methods: The study included samples from 182 CHB patients from Jeddah; 13 samples with HBsAg negative were excluded. Samples were tested for HDV-Ab, viral RNA by reverse transcriptase–polymerase chain reaction (RT-PCR) in the HDV L-Ag region and sequence analysis. Results: The mean age of the participants was 44.36 years; 75.1% of the participants were Saudi nationals, 58% were males. Nine samples were positive for HDV-Ab and four were borderline; all were subjected to RT-PCR amplification. Three of the positive HDV-Ab cases and 1 borderline case were positive by RT-PCR. All the positive cases had HBV genotype D, and the positive RT-PCR cases were positive for HBV DNA. One of the HDV viremic samples was of genotype 1 by sequencing. The prevalence of HDV in the study was 7.7%, which was lower in Saudis (6.3%) than in non-Saudis (11.9%). Conclusion: HDV coinfection does not seem to have an effect on the clinical status of the recruited CHB cases in this study. More studies are needed to investigate the genetic diversity in other areas such as the southern parts of the Kingdom." @default.
• W2729381590 created "2017-07-14" @default.
• W2729381590 creator A5010627878 @default.
• W2729381590 creator A5014120455 @default.
• W2729381590 creator A5042216877 @default.
• W2729381590 creator A5045993854 @default.
• W2729381590 creator A5060769590 @default.
• W2729381590 creator A5066972706 @default.
• W2729381590 creator A5068362077 @default.
• W2729381590 creator A5072690621 @default.
• W2729381590 creator A5073398298 @default.
• W2729381590 creator A5074026417 @default.
• W2729381590 creator A5077416714 @default.
• W2729381590 date "2017-01-01" @default.
• W2729381590 modified "2023-10-16" @default.
• W2729381590 title "Prevalence and molecular characterization of hepatitis D virus in Saudi Arabia: A single-center study" @default.
• W2729381590 cites W119762197 @default.
• W2729381590 cites W1955129002 @default.
• W2729381590 cites W1985901361 @default.
• W2729381590 cites W1988986320 @default.
• W2729381590 cites W1998150868 @default.
• W2729381590 cites W1999148628 @default.
• W2729381590 cites W2014070629 @default.
• W2729381590 cites W2050167026 @default.
• W2729381590 cites W2053151098 @default.
• W2729381590 cites W2068729256 @default.
• W2729381590 cites W2084397376 @default.
• W2729381590 cites W2089671189 @default.
• W2729381590 cites W2095804724 @default.
• W2729381590 cites W2095895939 @default.
• W2729381590 cites W2102875714 @default.
• W2729381590 cites W2122514369 @default.
• W2729381590 cites W2128880918 @default.
• W2729381590 cites W2132822415 @default.
• W2729381590 cites W2136377516 @default.
• W2729381590 cites W2144115844 @default.
• W2729381590 cites W2146115643 @default.
• W2729381590 cites W2152207030 @default.
• W2729381590 cites W2152575791 @default.
• W2729381590 cites W2158953615 @default.
• W2729381590 cites W215985599 @default.
• W2729381590 cites W2164833599 @default.
• W2729381590 cites W2172044291 @default.
• W2729381590 cites W2183209570 @default.
• W2729381590 cites W2252463042 @default.
• W2729381590 cites W2413058375 @default.
• W2729381590 cites W4238064113 @default.
• W2729381590 cites W2234492377 @default.
• W2729381590 doi "https://doi.org/10.4103/sjg.sjg_515_16" @default.
• W2729381590 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5470377" @default.
• W2729381590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28611341" @default.
• W2729381590 hasPublicationYear "2017" @default.
• W2729381590 type Work @default.
• W2729381590 sameAs 2729381590 @default.
• W2729381590 citedByCount "3" @default.
• W2729381590 countsByYear W27293815902019 @default.
• W2729381590 countsByYear W27293815902022 @default.
• W2729381590 countsByYear W27293815902023 @default.
• W2729381590 crossrefType "journal-article" @default.
• W2729381590 hasAuthorship W2729381590A5010627878 @default.
• W2729381590 hasAuthorship W2729381590A5014120455 @default.
• W2729381590 hasAuthorship W2729381590A5042216877 @default.
• W2729381590 hasAuthorship W2729381590A5045993854 @default.
• W2729381590 hasAuthorship W2729381590A5060769590 @default.
• W2729381590 hasAuthorship W2729381590A5066972706 @default.
• W2729381590 hasAuthorship W2729381590A5068362077 @default.
• W2729381590 hasAuthorship W2729381590A5072690621 @default.
• W2729381590 hasAuthorship W2729381590A5073398298 @default.
• W2729381590 hasAuthorship W2729381590A5074026417 @default.
• W2729381590 hasAuthorship W2729381590A5077416714 @default.
• W2729381590 hasBestOaLocation W27293815901 @default.
• W2729381590 hasConcept C104317684 @default.
• W2729381590 hasConcept C119599485 @default.
• W2729381590 hasConcept C127413603 @default.
• W2729381590 hasConcept C135763542 @default.
• W2729381590 hasConcept C159047783 @default.
• W2729381590 hasConcept C159654299 @default.
• W2729381590 hasConcept C203014093 @default.
• W2729381590 hasConcept C22070199 @default.
• W2729381590 hasConcept C2522874641 @default.
• W2729381590 hasConcept C2776699657 @default.
• W2729381590 hasConcept C2777382497 @default.
• W2729381590 hasConcept C2777410769 @default.
• W2729381590 hasConcept C2780593183 @default.
• W2729381590 hasConcept C2908737250 @default.
• W2729381590 hasConcept C45189115 @default.
• W2729381590 hasConcept C49105822 @default.
• W2729381590 hasConcept C55493867 @default.
• W2729381590 hasConcept C71924100 @default.
• W2729381590 hasConcept C761482 @default.
• W2729381590 hasConcept C86803240 @default.
• W2729381590 hasConceptScore W2729381590C104317684 @default.
• W2729381590 hasConceptScore W2729381590C119599485 @default.
• W2729381590 hasConceptScore W2729381590C127413603 @default.
• W2729381590 hasConceptScore W2729381590C135763542 @default.
• W2729381590 hasConceptScore W2729381590C159047783 @default.
• W2729381590 hasConceptScore W2729381590C159654299 @default.
• W2729381590 hasConceptScore W2729381590C203014093 @default.

• next