FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2729424069> ?p ?o ?g. }

• W2729424069 abstract "Tumor angiogenesis is a multiphasic process, having the extracellular matrix remodeling as critical step. Different classes of proteolytic enzymes in matrix digestion/remodeling are involved. The role of lytic enzymes and their activation mode have not been completely elucidated. Herein, the crosstalk between endothelia and tumor cells, by realization of bi- and three-dimensional endothelial and breast cancer cells co-cultures, were studied in vitro. Particularly, the effects of two tumor conditioned media (TCM) were assessed about endothelial proliferation, migration, and invasiveness. An increase in expression of pro-MMP9 was detected when endothelial cells were cultured in the presence of both TCM; such as an up-regulation of MMP1 and MMP14 and a down-regulation of MMP7. Moreover the increased MMP2 gene expression from one of them and the stimulation MMP3 synthesis from the other one were observed; an increases of β3-integrin, VEGFA, and DPP4 molecules were detected when endothelia cells are cultured with both TCM. The selection/characterization of elements present in conditioned media from breast cancer cells differently affect endothelial cells, make them potential effectors useful in breast cancer treatment." @default.
• W2729424069 created "2017-07-14" @default.
• W2729424069 creator A5017983636 @default.
• W2729424069 creator A5052170368 @default.
• W2729424069 creator A5054380274 @default.
• W2729424069 date "2017-08-15" @default.
• W2729424069 modified "2023-09-24" @default.
• W2729424069 title "MDA-MB-231 and 8701BC breast cancer lines promote the migration and invasiveness of ECV304 cells on 2D and 3D type-I collagen matrix" @default.
• W2729424069 cites W1961425572 @default.
• W2729424069 cites W1970421475 @default.
• W2729424069 cites W1979700784 @default.
• W2729424069 cites W1987245481 @default.
• W2729424069 cites W1995168398 @default.
• W2729424069 cites W2010666032 @default.
• W2729424069 cites W2034285427 @default.
• W2729424069 cites W2040888996 @default.
• W2729424069 cites W2050499474 @default.
• W2729424069 cites W2054838993 @default.
• W2729424069 cites W2060438764 @default.
• W2729424069 cites W2063380069 @default.
• W2729424069 cites W2072103796 @default.
• W2729424069 cites W2095893831 @default.
• W2729424069 cites W2100837269 @default.
• W2729424069 cites W2115294768 @default.
• W2729424069 cites W2123114542 @default.
• W2729424069 cites W2131420129 @default.
• W2729424069 cites W2144707486 @default.
• W2729424069 cites W2147000598 @default.
• W2729424069 cites W2152750025 @default.
• W2729424069 cites W2154803239 @default.
• W2729424069 cites W2165070344 @default.
• W2729424069 cites W2238879479 @default.
• W2729424069 cites W2296831383 @default.
• W2729424069 cites W4242396377 @default.
• W2729424069 doi "https://doi.org/10.1002/cbin.10817" @default.
• W2729424069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28678446" @default.
• W2729424069 hasPublicationYear "2017" @default.
• W2729424069 type Work @default.
• W2729424069 sameAs 2729424069 @default.
• W2729424069 citedByCount "3" @default.
• W2729424069 countsByYear W27294240692017 @default.
• W2729424069 countsByYear W27294240692019 @default.
• W2729424069 countsByYear W27294240692021 @default.
• W2729424069 crossrefType "journal-article" @default.
• W2729424069 hasAuthorship W2729424069A5017983636 @default.
• W2729424069 hasAuthorship W2729424069A5052170368 @default.
• W2729424069 hasAuthorship W2729424069A5054380274 @default.
• W2729424069 hasConcept C104317684 @default.
• W2729424069 hasConcept C120665830 @default.
• W2729424069 hasConcept C121332964 @default.
• W2729424069 hasConcept C121608353 @default.
• W2729424069 hasConcept C127561419 @default.
• W2729424069 hasConcept C129527566 @default.
• W2729424069 hasConcept C1491633281 @default.
• W2729424069 hasConcept C150194340 @default.
• W2729424069 hasConcept C169822122 @default.
• W2729424069 hasConcept C185592680 @default.
• W2729424069 hasConcept C189165786 @default.
• W2729424069 hasConcept C195687474 @default.
• W2729424069 hasConcept C2775997469 @default.
• W2729424069 hasConcept C2779013556 @default.
• W2729424069 hasConcept C2779295440 @default.
• W2729424069 hasConcept C2780394083 @default.
• W2729424069 hasConcept C2780699576 @default.
• W2729424069 hasConcept C502942594 @default.
• W2729424069 hasConcept C530470458 @default.
• W2729424069 hasConcept C54355233 @default.
• W2729424069 hasConcept C55493867 @default.
• W2729424069 hasConcept C86803240 @default.
• W2729424069 hasConcept C95444343 @default.
• W2729424069 hasConcept C96232424 @default.
• W2729424069 hasConceptScore W2729424069C104317684 @default.
• W2729424069 hasConceptScore W2729424069C120665830 @default.
• W2729424069 hasConceptScore W2729424069C121332964 @default.
• W2729424069 hasConceptScore W2729424069C121608353 @default.
• W2729424069 hasConceptScore W2729424069C127561419 @default.
• W2729424069 hasConceptScore W2729424069C129527566 @default.
• W2729424069 hasConceptScore W2729424069C1491633281 @default.
• W2729424069 hasConceptScore W2729424069C150194340 @default.
• W2729424069 hasConceptScore W2729424069C169822122 @default.
• W2729424069 hasConceptScore W2729424069C185592680 @default.
• W2729424069 hasConceptScore W2729424069C189165786 @default.
• W2729424069 hasConceptScore W2729424069C195687474 @default.
• W2729424069 hasConceptScore W2729424069C2775997469 @default.
• W2729424069 hasConceptScore W2729424069C2779013556 @default.
• W2729424069 hasConceptScore W2729424069C2779295440 @default.
• W2729424069 hasConceptScore W2729424069C2780394083 @default.
• W2729424069 hasConceptScore W2729424069C2780699576 @default.
• W2729424069 hasConceptScore W2729424069C502942594 @default.
• W2729424069 hasConceptScore W2729424069C530470458 @default.
• W2729424069 hasConceptScore W2729424069C54355233 @default.
• W2729424069 hasConceptScore W2729424069C55493867 @default.
• W2729424069 hasConceptScore W2729424069C86803240 @default.
• W2729424069 hasConceptScore W2729424069C95444343 @default.
• W2729424069 hasConceptScore W2729424069C96232424 @default.
• W2729424069 hasFunder F4320322991 @default.
• W2729424069 hasLocation W27294240691 @default.
• W2729424069 hasLocation W27294240692 @default.
• W2729424069 hasOpenAccess W2729424069 @default.
• W2729424069 hasPrimaryLocation W27294240691 @default.

• next