Matches in SemOpenAlex for { <https://semopenalex.org/work/W2729647568> ?p ?o ?g. }
- W2729647568 endingPage "66413" @default.
- W2729647568 startingPage "66402" @default.
- W2729647568 abstract "The diagnostic value and suitability of circulating miRNAs for the detection of hepatocellular carcinoma have been inconsistent in the literature. A meta-analysis is used to systematically evaluate the diagnostic value of circulating miRNAs. Eligible studies were selected and the heterogeneity was assessed by subgroup analysis, meta-regression, and publication bias. After strictly and comprehensive screening, the source methods, internal reference and the cut-off values of the included miRNAs were first listed. Circulating miRNAs demonstrated a relatively good diagnostic value in hepatocellular carcinoma, In the subgroup analysis, diagnosis odds ratio showed a higher accuracy with multiple miRNAs than with a single miRNA as well as with serum types than plasma types. In addition, although miRNAs have many expression patterns, the high frequency expression miRNAs (miR-21, miR-199 and miR-122) might be more specific for the diagnosis of hepatocellular carcinoma.The sources of heterogeneity might be related to the number of miRNAs and the specimen types in meta-regression. Furthermore, it's surprised that the pooled studies were first demonstrated publication bias (P < 0.05). In conclusion, multiple miRNAs in serum have a better diagnostic value, and the publication bias was stable. To validate the potential applicability of miRNAs in the diagnosis of hepatocellular carcinoma, more rigorous studies are needed to confirm these conclusions." @default.
- W2729647568 created "2017-07-14" @default.
- W2729647568 creator A5013201365 @default.
- W2729647568 creator A5044250956 @default.
- W2729647568 creator A5079246723 @default.
- W2729647568 creator A5083630702 @default.
- W2729647568 creator A5087549366 @default.
- W2729647568 date "2017-07-04" @default.
- W2729647568 modified "2023-10-17" @default.
- W2729647568 title "Circulating miRNAs as novel diagnostic biomarkers in hepatocellular carcinoma detection: a meta-analysis based on 24 articles" @default.
- W2729647568 cites W1524227817 @default.
- W2729647568 cites W1527284010 @default.
- W2729647568 cites W1568610635 @default.
- W2729647568 cites W1607954367 @default.
- W2729647568 cites W1648301895 @default.
- W2729647568 cites W1713786852 @default.
- W2729647568 cites W1757407923 @default.
- W2729647568 cites W1842957263 @default.
- W2729647568 cites W1904256709 @default.
- W2729647568 cites W1943870611 @default.
- W2729647568 cites W1975434185 @default.
- W2729647568 cites W1983142022 @default.
- W2729647568 cites W1985706360 @default.
- W2729647568 cites W1989941644 @default.
- W2729647568 cites W1991901646 @default.
- W2729647568 cites W1997924613 @default.
- W2729647568 cites W1999990472 @default.
- W2729647568 cites W2000307707 @default.
- W2729647568 cites W2000439481 @default.
- W2729647568 cites W2012522143 @default.
- W2729647568 cites W2020488794 @default.
- W2729647568 cites W2022173924 @default.
- W2729647568 cites W2024206172 @default.
- W2729647568 cites W2029807548 @default.
- W2729647568 cites W2033324112 @default.
- W2729647568 cites W2037688113 @default.
- W2729647568 cites W2039936569 @default.
- W2729647568 cites W2049047145 @default.
- W2729647568 cites W2051678809 @default.
- W2729647568 cites W2061701311 @default.
- W2729647568 cites W2061764944 @default.
- W2729647568 cites W2065130273 @default.
- W2729647568 cites W2066855314 @default.
- W2729647568 cites W2069660208 @default.
- W2729647568 cites W2090213127 @default.
- W2729647568 cites W2092926517 @default.
- W2729647568 cites W2096066755 @default.
- W2729647568 cites W2096621534 @default.
- W2729647568 cites W2097233439 @default.
- W2729647568 cites W2101110526 @default.
- W2729647568 cites W2107290223 @default.
- W2729647568 cites W2107638293 @default.
- W2729647568 cites W2111456931 @default.
- W2729647568 cites W2112785261 @default.
- W2729647568 cites W2118257856 @default.
- W2729647568 cites W2125435699 @default.
- W2729647568 cites W2125974265 @default.
- W2729647568 cites W2128754709 @default.
- W2729647568 cites W2136362813 @default.
- W2729647568 cites W2141680358 @default.
- W2729647568 cites W2144373793 @default.
- W2729647568 cites W2145720555 @default.
- W2729647568 cites W2146940151 @default.
- W2729647568 cites W2148923243 @default.
- W2729647568 cites W2158846712 @default.
- W2729647568 cites W2159343208 @default.
- W2729647568 cites W2162769953 @default.
- W2729647568 cites W2163486683 @default.
- W2729647568 cites W2169489859 @default.
- W2729647568 cites W2180345018 @default.
- W2729647568 cites W2181186034 @default.
- W2729647568 cites W2190153870 @default.
- W2729647568 cites W2228893886 @default.
- W2729647568 cites W2307710978 @default.
- W2729647568 cites W2490182863 @default.
- W2729647568 cites W2591717879 @default.
- W2729647568 doi "https://doi.org/10.18632/oncotarget.18949" @default.
- W2729647568 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5630422" @default.
- W2729647568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29029522" @default.
- W2729647568 hasPublicationYear "2017" @default.
- W2729647568 type Work @default.
- W2729647568 sameAs 2729647568 @default.
- W2729647568 citedByCount "32" @default.
- W2729647568 countsByYear W27296475682018 @default.
- W2729647568 countsByYear W27296475682019 @default.
- W2729647568 countsByYear W27296475682020 @default.
- W2729647568 countsByYear W27296475682021 @default.
- W2729647568 countsByYear W27296475682022 @default.
- W2729647568 countsByYear W27296475682023 @default.
- W2729647568 crossrefType "journal-article" @default.
- W2729647568 hasAuthorship W2729647568A5013201365 @default.
- W2729647568 hasAuthorship W2729647568A5044250956 @default.
- W2729647568 hasAuthorship W2729647568A5079246723 @default.
- W2729647568 hasAuthorship W2729647568A5083630702 @default.
- W2729647568 hasAuthorship W2729647568A5087549366 @default.
- W2729647568 hasBestOaLocation W27296475681 @default.
- W2729647568 hasConcept C104317684 @default.
- W2729647568 hasConcept C121608353 @default.