Matches in SemOpenAlex for { <https://semopenalex.org/work/W2730468694> ?p ?o ?g. }
- W2730468694 endingPage "4236" @default.
- W2730468694 startingPage "4225" @default.
- W2730468694 abstract "A novel design strategy for cocrystals of the diuretic sulfonamide drug bumetanide (BUM) with carboxamides is reported based on reliable supramolecular synthons. Binary cocrystals of BUM with pyridine carboxamides, pyridones, and cytosine were obtained by solvent-assisted grinding followed by solution crystallization. All cocrystal structures exhibit hydrogen bonding of the coformer with the carboxylic acid group of BUM via heterosynthons which replace the acid homodimer in the drug crystal structure. Pyridones are inserted as N–H···O dimers which are in turn bonded to the acid group of BUM, while the pyridine amide coformers interact via the acid–amide heterosynthon. Cocrystal polymorphs were obtained for bumetanide–isonicotinamide cocrystal structure with the sulfonamide–pyridine and sulfonamide–acid synthons. Careful crystal packing analysis of BUM structure and nine new binary adducts gave an idea for the design ternary cocrystals, and subsequently four new ternary crystalline products were crystalliz..." @default.
- W2730468694 created "2017-07-14" @default.
- W2730468694 creator A5003712646 @default.
- W2730468694 creator A5012058985 @default.
- W2730468694 creator A5013495432 @default.
- W2730468694 creator A5088712818 @default.
- W2730468694 date "2017-07-13" @default.
- W2730468694 modified "2023-10-17" @default.
- W2730468694 title "Supramolecular Synthons in Bumetanide Cocrystals and Ternary Products" @default.
- W2730468694 cites W1861200866 @default.
- W2730468694 cites W1965197146 @default.
- W2730468694 cites W1970288803 @default.
- W2730468694 cites W1972220131 @default.
- W2730468694 cites W1973034440 @default.
- W2730468694 cites W1986764614 @default.
- W2730468694 cites W1990936649 @default.
- W2730468694 cites W1998920258 @default.
- W2730468694 cites W2004922260 @default.
- W2730468694 cites W2007068681 @default.
- W2730468694 cites W2024703752 @default.
- W2730468694 cites W2025467708 @default.
- W2730468694 cites W2028993058 @default.
- W2730468694 cites W2030689418 @default.
- W2730468694 cites W2034106884 @default.
- W2730468694 cites W2052580375 @default.
- W2730468694 cites W2056706988 @default.
- W2730468694 cites W2067129640 @default.
- W2730468694 cites W2074947906 @default.
- W2730468694 cites W2075732573 @default.
- W2730468694 cites W2075760504 @default.
- W2730468694 cites W2083173953 @default.
- W2730468694 cites W2093276079 @default.
- W2730468694 cites W2093826313 @default.
- W2730468694 cites W2098031243 @default.
- W2730468694 cites W2098578488 @default.
- W2730468694 cites W2105726585 @default.
- W2730468694 cites W2117427401 @default.
- W2730468694 cites W2126069245 @default.
- W2730468694 cites W2127137961 @default.
- W2730468694 cites W2146886080 @default.
- W2730468694 cites W2166689829 @default.
- W2730468694 cites W2171280028 @default.
- W2730468694 cites W2307894086 @default.
- W2730468694 cites W2334162884 @default.
- W2730468694 cites W2335428606 @default.
- W2730468694 cites W2356915594 @default.
- W2730468694 cites W2519746541 @default.
- W2730468694 doi "https://doi.org/10.1021/acs.cgd.7b00531" @default.
- W2730468694 hasPublicationYear "2017" @default.
- W2730468694 type Work @default.
- W2730468694 sameAs 2730468694 @default.
- W2730468694 citedByCount "24" @default.
- W2730468694 countsByYear W27304686942018 @default.
- W2730468694 countsByYear W27304686942019 @default.
- W2730468694 countsByYear W27304686942020 @default.
- W2730468694 countsByYear W27304686942021 @default.
- W2730468694 countsByYear W27304686942022 @default.
- W2730468694 countsByYear W27304686942023 @default.
- W2730468694 crossrefType "journal-article" @default.
- W2730468694 hasAuthorship W2730468694A5003712646 @default.
- W2730468694 hasAuthorship W2730468694A5012058985 @default.
- W2730468694 hasAuthorship W2730468694A5013495432 @default.
- W2730468694 hasAuthorship W2730468694A5088712818 @default.
- W2730468694 hasConcept C100687433 @default.
- W2730468694 hasConcept C112887158 @default.
- W2730468694 hasConcept C115624301 @default.
- W2730468694 hasConcept C171250308 @default.
- W2730468694 hasConcept C178790620 @default.
- W2730468694 hasConcept C185592680 @default.
- W2730468694 hasConcept C192562407 @default.
- W2730468694 hasConcept C199360897 @default.
- W2730468694 hasConcept C21951064 @default.
- W2730468694 hasConcept C32909587 @default.
- W2730468694 hasConcept C40869318 @default.
- W2730468694 hasConcept C41008148 @default.
- W2730468694 hasConcept C64452783 @default.
- W2730468694 hasConcept C71240020 @default.
- W2730468694 hasConcept C93275456 @default.
- W2730468694 hasConceptScore W2730468694C100687433 @default.
- W2730468694 hasConceptScore W2730468694C112887158 @default.
- W2730468694 hasConceptScore W2730468694C115624301 @default.
- W2730468694 hasConceptScore W2730468694C171250308 @default.
- W2730468694 hasConceptScore W2730468694C178790620 @default.
- W2730468694 hasConceptScore W2730468694C185592680 @default.
- W2730468694 hasConceptScore W2730468694C192562407 @default.
- W2730468694 hasConceptScore W2730468694C199360897 @default.
- W2730468694 hasConceptScore W2730468694C21951064 @default.
- W2730468694 hasConceptScore W2730468694C32909587 @default.
- W2730468694 hasConceptScore W2730468694C40869318 @default.
- W2730468694 hasConceptScore W2730468694C41008148 @default.
- W2730468694 hasConceptScore W2730468694C64452783 @default.
- W2730468694 hasConceptScore W2730468694C71240020 @default.
- W2730468694 hasConceptScore W2730468694C93275456 @default.
- W2730468694 hasFunder F4320320721 @default.
- W2730468694 hasFunder F4320334771 @default.
- W2730468694 hasIssue "8" @default.
- W2730468694 hasLocation W27304686941 @default.
- W2730468694 hasOpenAccess W2730468694 @default.