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- W2732456988 abstract "Objective: This study aimed to determine the prevalence of hypothyroidism and its association with menopausal symptoms. We evaluated the diagnostic performance of Zulewski’s clinical score for hypothyroidism. Material and Method : This study was conducted between June 2015 and April 2016 in Khon Kaen, Thailand. This was a hospital-based cross-sectional analytical study. We enrolled 305 menopausal women 45-65 years of age with no previous history of thyroid diseases, no radiation exposure at the neck, and no concurrent use of lithium. The participants were interviewed by two research assistants’ vis-a-vis symptoms of menopause, hypothyroidism, medications taken and menstrual bleeding characteristics. Blood samples were taken for TSH and FT4 levels. Main outcomes were prevalence of hypothyroidism, MENQOL score, and diagnostic performance of Zulewski’s clinical score. Stata version 10.0 was used for the statistical analyses. Results: Mean age was 56 + 4.7years. The prevalence of hypothyroidism in the menopausal women was 6.23% (95%CI 3.52% to 8.94%). The sensitivity of Zulewski’s clinical score at the cutoff point > 3 was 70%. Neither a composite nor any other MENQOL domain score was associated with hypothyroidism. Conclusion: In light of the findings, TSH screening in menopausal women is pointless and Zulewski’s clinical score is not a good screening test for hypothyroidism in this group. Key words: menopausal women, hypothyroidism, Zulewski’s clinical score" @default.
- W2732456988 created "2017-07-14" @default.
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- W2732456988 date "2017-12-30" @default.
- W2732456988 modified "2023-09-23" @default.
- W2732456988 title "Hypothyroidism in Menopausal Women: A Cross-sectional Analytical Study" @default.
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