Matches in SemOpenAlex for { <https://semopenalex.org/work/W2732474814> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2732474814 abstract "1566 Background: Familial Mediterranean fever (FMF) is an autoinflammatory disease that causes recurrent serosal inflammation. The association between FMF and malignancy has not been previously described. We estimated cancer risk in a large single-institution cohort of FMF patients. Methods: The study cohort consisted of 8,534 FMF patients registered in the Israel National FMF Center at Tel Hashomer, Israel. We linked the study cohort to the database of the Israel National Cancer Registry using the national identity number. Cancer incidence in FMF patients was determined and stratified by age and gender. Standardized incidence ratios (SIR) for cancers were calculated. Results: Among 8,534 FMF patients (4,400 men, 4,134 women), 350 developed cancer during the years 1970-2011. Overall cancer risk among patients with FMF was significantly lower than that expected in the following gender and population groups, based on cancer incidence rates in those groups in the Israeli population: males of Jewish ethnicity SIR 0.66, CI 95% [0.55-0.77], p< 0.001; females of Jewish ethnicity SIR 0.75 CI 95% [0.64-0.86], p< 0.001; males of Arabic ethnicity SIR 0.34, CI 95% [0.07-0.99], p= 0.024. Conclusions: FMF patients have a significantly lower incidence of cancer than the general population. This pattern was demonstrated in two different ethnic populations, Jewish and Arabic. We speculate that the lower cancer incidence could be attributed to the direct physiological effect of FMF or to the anti-FMF treatment." @default.
- W2732474814 created "2017-07-14" @default.
- W2732474814 creator A5020903489 @default.
- W2732474814 date "2017-05-20" @default.
- W2732474814 modified "2023-09-27" @default.
- W2732474814 title "Anti-cancer effect among patients with familial Mediterranean fever: Outcome of 258,803 person-years analysis." @default.
- W2732474814 doi "https://doi.org/10.1200/jco.2017.35.15_suppl.1566" @default.
- W2732474814 hasPublicationYear "2017" @default.
- W2732474814 type Work @default.
- W2732474814 sameAs 2732474814 @default.
- W2732474814 citedByCount "0" @default.
- W2732474814 crossrefType "journal-article" @default.
- W2732474814 hasAuthorship W2732474814A5020903489 @default.
- W2732474814 hasConcept C121608353 @default.
- W2732474814 hasConcept C126322002 @default.
- W2732474814 hasConcept C143998085 @default.
- W2732474814 hasConcept C144024400 @default.
- W2732474814 hasConcept C144237770 @default.
- W2732474814 hasConcept C148220186 @default.
- W2732474814 hasConcept C149923435 @default.
- W2732474814 hasConcept C2779134260 @default.
- W2732474814 hasConcept C2779537928 @default.
- W2732474814 hasConcept C33923547 @default.
- W2732474814 hasConcept C71924100 @default.
- W2732474814 hasConceptScore W2732474814C121608353 @default.
- W2732474814 hasConceptScore W2732474814C126322002 @default.
- W2732474814 hasConceptScore W2732474814C143998085 @default.
- W2732474814 hasConceptScore W2732474814C144024400 @default.
- W2732474814 hasConceptScore W2732474814C144237770 @default.
- W2732474814 hasConceptScore W2732474814C148220186 @default.
- W2732474814 hasConceptScore W2732474814C149923435 @default.
- W2732474814 hasConceptScore W2732474814C2779134260 @default.
- W2732474814 hasConceptScore W2732474814C2779537928 @default.
- W2732474814 hasConceptScore W2732474814C33923547 @default.
- W2732474814 hasConceptScore W2732474814C71924100 @default.
- W2732474814 hasLocation W27324748141 @default.
- W2732474814 hasOpenAccess W2732474814 @default.
- W2732474814 hasPrimaryLocation W27324748141 @default.
- W2732474814 hasRelatedWork W1588791301 @default.
- W2732474814 hasRelatedWork W1967366139 @default.
- W2732474814 hasRelatedWork W2019555509 @default.
- W2732474814 hasRelatedWork W2021969096 @default.
- W2732474814 hasRelatedWork W2048389142 @default.
- W2732474814 hasRelatedWork W2075117246 @default.
- W2732474814 hasRelatedWork W2122237679 @default.
- W2732474814 hasRelatedWork W2134222321 @default.
- W2732474814 hasRelatedWork W2150557085 @default.
- W2732474814 hasRelatedWork W2229424225 @default.
- W2732474814 hasRelatedWork W2400225289 @default.
- W2732474814 hasRelatedWork W2401840978 @default.
- W2732474814 hasRelatedWork W2405226752 @default.
- W2732474814 hasRelatedWork W2425937706 @default.
- W2732474814 hasRelatedWork W2947396968 @default.
- W2732474814 hasRelatedWork W2979425303 @default.
- W2732474814 hasRelatedWork W2981545743 @default.
- W2732474814 hasRelatedWork W2997406210 @default.
- W2732474814 hasRelatedWork W3003544202 @default.
- W2732474814 hasRelatedWork W3163648932 @default.
- W2732474814 isParatext "false" @default.
- W2732474814 isRetracted "false" @default.
- W2732474814 magId "2732474814" @default.
- W2732474814 workType "article" @default.