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- W2732836228 abstract "Introduction Though prescription is off-lable, “atypical” or “second-generation” antipsychotics (SGAs) are prevalently given to borderline personality disorder (BPD) patients. They have also been the focus of research on pharmacological agents in BPD in recent years, as the previous version of the relating cochrane systematic review shows. Objectives We are currently updating this cochrane systematic review on pharmacological interventions for BPD. First findings on the up-to-date evidence relating to SGAs will be presented. Methods We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) according to cochrane collaboration standards. Any randomized comparisons of drug vs. placebo, drug vs. drug, or drug vs. a combination of drugs in adult BPD patients were eligible. Primary outcomes were BPD core pathology as depicted by DSM criteria. Secondary outcomes included associated pathology, i.e., depression and anxiety, general psychopathology severity and functioning as well as tolerability and safety. Two researchers selected trials, assessed quality and extracted data independently. Results The current RCT evidence on SGAs in BPD will be presented, and their use in everyday clinical care settings will critically be discussed. Disclosure of interest The authors declare that they have no competing interest." @default.
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- W2732836228 date "2017-04-01" @default.
- W2732836228 modified "2023-09-28" @default.
- W2732836228 title "Effectiveness of Antipsychotic Medication in the Treatment of BPD" @default.
- W2732836228 doi "https://doi.org/10.1016/j.eurpsy.2017.01.204" @default.
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