FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2733352015> ?p ?o ?g. }

• W2733352015 abstract "Using a genome-wide association study strategy, our previous study discovered 19 significant single-nucleotide polymorphisms (SNPs) related to semen production traits in Chinese Holstein bulls. Among them, three SNPs were within or close to the phosphodiesterase 3A (PDE3A), membrane associated ring-CH-type finger 1 (MARCH1) and platelet derived growth factor receptor beta (PDGFRB) genes. The present study was designed with the objectives of identifying genetic polymorphism of the PDE3A, PDGFRB and MARCH1 genes and their effects on semen production traits in a Holstein bull population. A total of 20 SNPs were detected and genotyped in 730 bulls. Association analyses using de-regressed estimated breeding values of each semen production trait revealed four statistically significant SNPs for one or more semen production traits (P < 0.05): one SNP was located downstream of PDGFRB and three SNPs were located in the promoter of MARCH1. Interestingly, for MARCH1, haplotype-based analysis revealed significant associations of haplotypes with semen volume per ejaculate. Furthermore, high expression of the MARCH1 gene was observed in sperm cells. One SNP (rs43445726) in the regulatory region of MARCH1 had a significant effect on gene expression. Our study demonstrated the significant associations of genetic variants of the PDGFRB and MARCH1 genes with semen production traits. The identified SNPs may serve as genetic markers to optimize breeding programs for semen production traits in Holstein bull populations." @default.
• W2733352015 created "2017-07-14" @default.
• W2733352015 creator A5018090532 @default.
• W2733352015 creator A5024595001 @default.
• W2733352015 creator A5034413459 @default.
• W2733352015 creator A5037711123 @default.
• W2733352015 creator A5059463745 @default.
• W2733352015 creator A5077257686 @default.
• W2733352015 creator A5086200083 @default.
• W2733352015 date "2017-07-03" @default.
• W2733352015 modified "2023-10-09" @default.
• W2733352015 title "Genetic effects of PDGFRB and MARCH1 identified in GWAS revealing strong associations with semen production traits in Chinese Holstein bulls" @default.
• W2733352015 cites W1885740864 @default.
• W2733352015 cites W1979577318 @default.
• W2733352015 cites W1985658715 @default.
• W2733352015 cites W1994425444 @default.
• W2733352015 cites W2010898616 @default.
• W2733352015 cites W2021066535 @default.
• W2733352015 cites W2023258903 @default.
• W2733352015 cites W2024499633 @default.
• W2733352015 cites W2025239273 @default.
• W2733352015 cites W2030588393 @default.
• W2733352015 cites W2034750386 @default.
• W2733352015 cites W2040583830 @default.
• W2733352015 cites W2058263689 @default.
• W2733352015 cites W2065192577 @default.
• W2733352015 cites W2077622162 @default.
• W2733352015 cites W2078338257 @default.
• W2733352015 cites W2083808803 @default.
• W2733352015 cites W2085995830 @default.
• W2733352015 cites W2089811846 @default.
• W2733352015 cites W2093559422 @default.
• W2733352015 cites W2096060324 @default.
• W2733352015 cites W2098866515 @default.
• W2733352015 cites W2110974472 @default.
• W2733352015 cites W2139897727 @default.
• W2733352015 cites W2143555296 @default.
• W2733352015 cites W2146606306 @default.
• W2733352015 cites W2152664025 @default.
• W2733352015 cites W2162530578 @default.
• W2733352015 cites W2304210406 @default.
• W2733352015 cites W2419343487 @default.
• W2733352015 cites W2516297784 @default.
• W2733352015 cites W2520604988 @default.
• W2733352015 cites W3150434257 @default.
• W2733352015 doi "https://doi.org/10.1186/s12863-017-0527-1" @default.
• W2733352015 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5496367" @default.
• W2733352015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28673243" @default.
• W2733352015 hasPublicationYear "2017" @default.
• W2733352015 type Work @default.
• W2733352015 sameAs 2733352015 @default.
• W2733352015 citedByCount "26" @default.
• W2733352015 countsByYear W27333520152018 @default.
• W2733352015 countsByYear W27333520152019 @default.
• W2733352015 countsByYear W27333520152020 @default.
• W2733352015 countsByYear W27333520152021 @default.
• W2733352015 countsByYear W27333520152022 @default.
• W2733352015 countsByYear W27333520152023 @default.
• W2733352015 crossrefType "journal-article" @default.
• W2733352015 hasAuthorship W2733352015A5018090532 @default.
• W2733352015 hasAuthorship W2733352015A5024595001 @default.
• W2733352015 hasAuthorship W2733352015A5034413459 @default.
• W2733352015 hasAuthorship W2733352015A5037711123 @default.
• W2733352015 hasAuthorship W2733352015A5059463745 @default.
• W2733352015 hasAuthorship W2733352015A5077257686 @default.
• W2733352015 hasAuthorship W2733352015A5086200083 @default.
• W2733352015 hasBestOaLocation W27333520151 @default.
• W2733352015 hasConcept C104317684 @default.
• W2733352015 hasConcept C106208931 @default.
• W2733352015 hasConcept C135763542 @default.
• W2733352015 hasConcept C139275648 @default.
• W2733352015 hasConcept C153209595 @default.
• W2733352015 hasConcept C180754005 @default.
• W2733352015 hasConcept C186413461 @default.
• W2733352015 hasConcept C197754878 @default.
• W2733352015 hasConcept C2778093475 @default.
• W2733352015 hasConcept C54355233 @default.
• W2733352015 hasConcept C69991583 @default.
• W2733352015 hasConcept C78221974 @default.
• W2733352015 hasConcept C86803240 @default.
• W2733352015 hasConceptScore W2733352015C104317684 @default.
• W2733352015 hasConceptScore W2733352015C106208931 @default.
• W2733352015 hasConceptScore W2733352015C135763542 @default.
• W2733352015 hasConceptScore W2733352015C139275648 @default.
• W2733352015 hasConceptScore W2733352015C153209595 @default.
• W2733352015 hasConceptScore W2733352015C180754005 @default.
• W2733352015 hasConceptScore W2733352015C186413461 @default.
• W2733352015 hasConceptScore W2733352015C197754878 @default.
• W2733352015 hasConceptScore W2733352015C2778093475 @default.
• W2733352015 hasConceptScore W2733352015C54355233 @default.
• W2733352015 hasConceptScore W2733352015C69991583 @default.
• W2733352015 hasConceptScore W2733352015C78221974 @default.
• W2733352015 hasConceptScore W2733352015C86803240 @default.
• W2733352015 hasIssue "1" @default.
• W2733352015 hasLocation W27333520151 @default.
• W2733352015 hasLocation W27333520152 @default.
• W2733352015 hasLocation W27333520153 @default.
• W2733352015 hasLocation W27333520154 @default.
• W2733352015 hasOpenAccess W2733352015 @default.
• W2733352015 hasPrimaryLocation W27333520151 @default.

• next