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- W27337516 abstract "The conditioned media of subconfluent and confluent monolayers of porcine astrocytes and different cell lines were used to reinduce in primary cultured endothelial cells of porcine brain microvessels in vivo properties like high activities of the marker enzymes alkaline phosphatase (ALP) and γ-glutamyltranspeptidase (γ-GT). After 7 days in culture, the activity of ALP increased only by incubation of cerebral endothelial cells with conditioned media from confluent adult porcine astrocytes and CHO-cells (fibroblasts), whereas the activity of γ-GT was significantly increased by conditioned media of astrocytes, CHOcells, chondrocytes and adenocarcinoma cells. However, the increase in γ-GT seems to be the result of an increase in the number of cells on the top of the monolayer with high γ-GT activities as revealed by histochemistry. The mechanism of the inductive effect on γ-GT seems to be not astrocyte specific and has to be clarified." @default.
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- W27337516 date "1996-01-01" @default.
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- W27337516 title "The Effect of Conditioned Medium of Porcine Astrocytes and Different Cell Lines on the Activity of the Marker Enzymes Alp and γ-GT in Endothelial Cells of Porcine Brain Microvessels" @default.
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- W27337516 doi "https://doi.org/10.1007/978-1-4757-9489-2_38" @default.
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