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• W2733865510 abstract "<h3>Objectives:</h3> To determine the seroprevalence of <i>Toxoplasma gondii</i> (<i>T. gondii</i>), Rubella virus, and Cytomegalovirus (CMV) among pregnant women in Izmir, Turkey. <h3>Methods:</h3> Medical records of pregnant women attending Izmir Tepecik Training and Research Hospital, Izmir, Turkey between January 2014 and January 2016 were analyzed in this retrospective cross-sectional study. The 7513 <i>T. gondii</i> IgM/IgG results, 7189 Rubella IgM/IgG results, 906 CMV IgM/IgG results and 146 avidity test results were evaluated. Specific IgM and IgG antibodies were detected by an automated chemiluminescent enzyme immunoassay method. Immunoglobulin G avidity tests were performed using a multiparametric immunoassay system. <h3>Results:</h3> The rates of IgG positivity for <i>T. gondii</i> was 32.3%, Rubella virus 93.5%, and CMV 98.9%. Immunoglobulin M antibodies were found to be positive in 138 (1.9%) cases for <i>T. gondii</i>, 88 (1.2%) cases for Rubella, and 14 (1.5%) cases for CMV. Avidity tests were ordered from 146 of 218 patients who were found both IgM and IgG positive. Among 146 patients, 6 patients had a low avidity index (all for <i>T. gondii</i>), 11 patients showed borderline avidity, and 129 patients revealed high avidity. <h3>Conclusion:</h3> In our region, whereas the rates of IgG positivity for Rubella and CMV are high, most pregnant women were susceptible to <i>T. gondii</i> infections. In order to enhance the reliability of the serological diagnosis, avidity tests should be performed in all IgM positivities detected together with IgG positivity." @default.
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• W2733865510 date "2017-07-01" @default.
• W2733865510 modified "2023-10-17" @default.
• W2733865510 title "Seroprevalence of <i>Toxoplasma gondii</i>, Rubella virus and Cytomegalovirus among pregnant women and the importance of avidity assays" @default.
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• W2733865510 doi "https://doi.org/10.15537/smj.2017.7.18182" @default.
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