Matches in SemOpenAlex for { <https://semopenalex.org/work/W2733996830> ?p ?o ?g. }
- W2733996830 endingPage "248" @default.
- W2733996830 startingPage "237" @default.
- W2733996830 abstract "In the last decades, it has been recognized that extracellular vesicles (EVs) are not only cell debris with no biological role, but instead they play a key role in information exchange between cells either in health and disease conditions. EVs exhibit indeed their biological role in a pleiotropic manner. They can modulate immune responses through the activation, transfer or removal of surface receptors on target cells, the removal of cytolytic components such as membrane attack complexes, and the transfer of signaling molecules/effectors, such as nucleic acid species, infectious particles, and oncogenes. Among the naturally-derived nanoparticles that have been developed in the last years, stimuli responsive exosomes drew special attention since they intrinsically possess many attributes of a desirable drug delivery system. Their small size allows them to bypass the mononuclear phagocytic system (MPS) clearance, thereby prolonging their circulation time for passive targeting to inflammatory tissues. Moreover, they can deliver their cargo directly into the cytosol, avoiding the lysosomal/endosomal pathway and thus, increasing the transfection efficiency when they are used as gene delivery systems. of This review offers the state of the art knowledge on the physiology and properties of EVs, namely, apoptotic vesicles, microvesicles and exosomes as innovative drug delivery systems for gene therapy, with a special focus on targeting dendritic cells for the treatment of autoimmune disorders." @default.
- W2733996830 created "2017-07-14" @default.
- W2733996830 creator A5008458501 @default.
- W2733996830 creator A5009381122 @default.
- W2733996830 creator A5023182854 @default.
- W2733996830 creator A5024837857 @default.
- W2733996830 creator A5047891641 @default.
- W2733996830 creator A5068585646 @default.
- W2733996830 date "2017-10-01" @default.
- W2733996830 modified "2023-10-12" @default.
- W2733996830 title "Targeting dendritic cells for the treatment of autoimmune disorders" @default.
- W2733996830 cites W1141087116 @default.
- W2733996830 cites W1497435349 @default.
- W2733996830 cites W1520693177 @default.
- W2733996830 cites W1526830066 @default.
- W2733996830 cites W1749515626 @default.
- W2733996830 cites W1758593549 @default.
- W2733996830 cites W1885020892 @default.
- W2733996830 cites W1964674962 @default.
- W2733996830 cites W1977560532 @default.
- W2733996830 cites W1979254251 @default.
- W2733996830 cites W1981087418 @default.
- W2733996830 cites W1985619179 @default.
- W2733996830 cites W1987523416 @default.
- W2733996830 cites W2000034106 @default.
- W2733996830 cites W2000121178 @default.
- W2733996830 cites W2004017043 @default.
- W2733996830 cites W2014179704 @default.
- W2733996830 cites W2015387324 @default.
- W2733996830 cites W2015818882 @default.
- W2733996830 cites W2031325281 @default.
- W2733996830 cites W2031750503 @default.
- W2733996830 cites W2046635218 @default.
- W2733996830 cites W2047521139 @default.
- W2733996830 cites W2051227487 @default.
- W2733996830 cites W2055313665 @default.
- W2733996830 cites W2059197379 @default.
- W2733996830 cites W2060387475 @default.
- W2733996830 cites W2065345621 @default.
- W2733996830 cites W2066234893 @default.
- W2733996830 cites W2068082819 @default.
- W2733996830 cites W2070070981 @default.
- W2733996830 cites W2071625709 @default.
- W2733996830 cites W2077170410 @default.
- W2733996830 cites W2079830794 @default.
- W2733996830 cites W2086167986 @default.
- W2733996830 cites W2088630594 @default.
- W2733996830 cites W2090525477 @default.
- W2733996830 cites W2091250479 @default.
- W2733996830 cites W2099831769 @default.
- W2733996830 cites W2101495492 @default.
- W2733996830 cites W2101588077 @default.
- W2733996830 cites W2106583271 @default.
- W2733996830 cites W2108528211 @default.
- W2733996830 cites W2120698857 @default.
- W2733996830 cites W2122635106 @default.
- W2733996830 cites W2124304994 @default.
- W2733996830 cites W2127514713 @default.
- W2733996830 cites W2127517948 @default.
- W2733996830 cites W2143044967 @default.
- W2733996830 cites W2150707647 @default.
- W2733996830 cites W2163912530 @default.
- W2733996830 cites W2165545496 @default.
- W2733996830 cites W2166846320 @default.
- W2733996830 cites W2168064787 @default.
- W2733996830 cites W2171471266 @default.
- W2733996830 cites W2177926460 @default.
- W2733996830 cites W2178935826 @default.
- W2733996830 cites W2180163807 @default.
- W2733996830 cites W2194131658 @default.
- W2733996830 cites W2234822502 @default.
- W2733996830 cites W2278555975 @default.
- W2733996830 cites W2278567201 @default.
- W2733996830 cites W2283913673 @default.
- W2733996830 cites W2290891464 @default.
- W2733996830 cites W2297506254 @default.
- W2733996830 cites W2320891287 @default.
- W2733996830 cites W2325305253 @default.
- W2733996830 cites W2338671470 @default.
- W2733996830 cites W2896692753 @default.
- W2733996830 cites W4251993943 @default.
- W2733996830 cites W54702936 @default.
- W2733996830 cites W824570847 @default.
- W2733996830 doi "https://doi.org/10.1016/j.colsurfb.2017.06.050" @default.
- W2733996830 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28697439" @default.
- W2733996830 hasPublicationYear "2017" @default.
- W2733996830 type Work @default.
- W2733996830 sameAs 2733996830 @default.
- W2733996830 citedByCount "18" @default.
- W2733996830 countsByYear W27339968302018 @default.
- W2733996830 countsByYear W27339968302019 @default.
- W2733996830 countsByYear W27339968302020 @default.
- W2733996830 countsByYear W27339968302021 @default.
- W2733996830 countsByYear W27339968302022 @default.
- W2733996830 countsByYear W27339968302023 @default.
- W2733996830 crossrefType "journal-article" @default.
- W2733996830 hasAuthorship W2733996830A5008458501 @default.
- W2733996830 hasAuthorship W2733996830A5009381122 @default.