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- W2734335979 abstract "<h3>Objectives</h3> Cerebral palsy (CP) remains the world’s most common childhood physical disability with total annual costs of care and lost well-being of $A3.87b. The PREDICT-CP (NHMRC 1077257 Partnership Project: Comprehensive surveillance to PREDICT outcomes for school age children with CP) study will investigate the influence of brain structure, body composition, dietary intake, oropharyngeal function, habitual physical activity, musculoskeletal development (hip status, bone health) and muscle performance on motor attainment, cognition, executive function, communication, participation, quality of life and related health resource use costs. The PREDICT-CP cohort provides further follow-up at 8–12 years of two overlapping preschool-age cohorts examined from 1.5 to 5 years (NHMRC 465128 motor and brain development; NHMRC 569605 growth, nutrition and physical activity). <h3>Methods and analyses</h3> This population-based cohort study undertakes state-wide surveillance of 245 children with CP born in Queensland (birth years 2006–2009). Children will be classified for Gross Motor Function Classification System; Manual Ability Classification System, Communication Function Classification System and Eating and Drinking Ability Classification System. Outcomes include gross motor function, musculoskeletal development (hip displacement, spasticity, muscle contracture), upper limb function, communication difficulties, oropharyngeal dysphagia, dietary intake and body composition, participation, parent-reported and child-reported quality of life and medical and allied health resource use. These detailed phenotypical data will be compared with brain macrostructure and microstructure using 3 Tesla MRI (3T MRI). Relationships between brain lesion severity and outcomes will be analysed using multilevel mixed-effects models. <h3>Ethics and dissemination</h3> The PREDICT-CP protocol is a prospectively registered and ethically accepted study protocol. The study combines data at 1.5–5 then 8–12 years of direct clinical assessment to enable prediction of outcomes and healthcare needs essential for tailoring interventions (eg, rehabilitation, orthopaedic surgery and nutritional supplements) and the projected healthcare utilisation. <h3>Trial registration number</h3> ACTRN: 12616001488493" @default.
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- W2734335979 date "2017-07-01" @default.
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- W2734335979 title "PREDICT-CP: study protocol of implementation of comprehensive surveillance to predict outcomes for school-aged children with cerebral palsy" @default.
- W2734335979 cites W1493182793 @default.
- W2734335979 cites W1505304836 @default.
- W2734335979 cites W152404302 @default.
- W2734335979 cites W1529458632 @default.
- W2734335979 cites W1538244561 @default.
- W2734335979 cites W1569163094 @default.
- W2734335979 cites W1582698249 @default.
- W2734335979 cites W1589750505 @default.
- W2734335979 cites W1592604299 @default.
- W2734335979 cites W1595606899 @default.
- W2734335979 cites W1617154394 @default.
- W2734335979 cites W164262269 @default.
- W2734335979 cites W1903544543 @default.
- W2734335979 cites W1963677157 @default.
- W2734335979 cites W1963996455 @default.
- W2734335979 cites W1964235976 @default.
- W2734335979 cites W1964895339 @default.
- W2734335979 cites W1965698180 @default.
- W2734335979 cites W1969519267 @default.
- W2734335979 cites W1973901357 @default.
- W2734335979 cites W1979683501 @default.
- W2734335979 cites W1980153570 @default.
- W2734335979 cites W1980652514 @default.
- W2734335979 cites W1987768016 @default.
- W2734335979 cites W1990166011 @default.
- W2734335979 cites W1990418860 @default.
- W2734335979 cites W1995856724 @default.
- W2734335979 cites W1996266923 @default.
- W2734335979 cites W1999934864 @default.
- W2734335979 cites W2000943144 @default.
- W2734335979 cites W2001611992 @default.
- W2734335979 cites W2005184890 @default.
- W2734335979 cites W2005733086 @default.
- W2734335979 cites W2007684928 @default.
- W2734335979 cites W2010989450 @default.
- W2734335979 cites W2011481459 @default.
- W2734335979 cites W2012632744 @default.
- W2734335979 cites W2013022229 @default.
- W2734335979 cites W2017165492 @default.
- W2734335979 cites W2017217079 @default.
- W2734335979 cites W2017431521 @default.
- W2734335979 cites W2017522865 @default.
- W2734335979 cites W2018916507 @default.
- W2734335979 cites W2018930150 @default.
- W2734335979 cites W2019904259 @default.
- W2734335979 cites W2022167001 @default.
- W2734335979 cites W2025330974 @default.
- W2734335979 cites W2025802167 @default.
- W2734335979 cites W2025844429 @default.
- W2734335979 cites W2027198870 @default.
- W2734335979 cites W2027217734 @default.
- W2734335979 cites W2028360958 @default.
- W2734335979 cites W2029168122 @default.
- W2734335979 cites W2030284365 @default.
- W2734335979 cites W2030750461 @default.
- W2734335979 cites W2031925226 @default.
- W2734335979 cites W2034431466 @default.
- W2734335979 cites W2034646657 @default.
- W2734335979 cites W2035516360 @default.
- W2734335979 cites W2035793658 @default.
- W2734335979 cites W2043282286 @default.