Matches in SemOpenAlex for { <https://semopenalex.org/work/W2734896670> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2734896670 abstract "There is a large sex difference in the prevalence of attention deficit disorder; yet, little is known about sex differences in prefrontal attention circuitry. We investigated sex differences in the developmental nicotinic excitation of corticothalamic layer VI neurons, which play an important role in attention. Using whole cell recording in prefrontal brain slices, we examined the inward currents elicited by nicotinic stimulation in rodents. We found a prominent sex difference in the currents during the first postnatal month when males had significantly greater α4β2* nicotinic currents. Immunohistochemical analysis of α4YFP mice revealed no sex difference in the pattern or proportion of YFP-positive neurons in layer VI. Further electrophysiological experiments revealed that progesterone is able to rapidly and significantly suppress nicotinic currents in layer VI neurons. This is the first illustration at a cellular level that prefrontal attention circuitry is differently excited by nicotinic stimulation in males and females during development.%%%%MAST" @default.
- W2734896670 created "2017-07-21" @default.
- W2734896670 creator A5066090715 @default.
- W2734896670 date "2009-12-14" @default.
- W2734896670 modified "2023-09-26" @default.
- W2734896670 title "Sex Differences in Nicotinic Currents of Layer VI Neurons of Prefrontal Cortex During Development" @default.
- W2734896670 hasPublicationYear "2009" @default.
- W2734896670 type Work @default.
- W2734896670 sameAs 2734896670 @default.
- W2734896670 citedByCount "0" @default.
- W2734896670 crossrefType "dissertation" @default.
- W2734896670 hasAuthorship W2734896670A5066090715 @default.
- W2734896670 hasConcept C126322002 @default.
- W2734896670 hasConcept C134018914 @default.
- W2734896670 hasConcept C15744967 @default.
- W2734896670 hasConcept C169760540 @default.
- W2734896670 hasConcept C169900460 @default.
- W2734896670 hasConcept C170493617 @default.
- W2734896670 hasConcept C185263204 @default.
- W2734896670 hasConcept C188987157 @default.
- W2734896670 hasConcept C24998067 @default.
- W2734896670 hasConcept C2781195155 @default.
- W2734896670 hasConcept C71924100 @default.
- W2734896670 hasConcept C86803240 @default.
- W2734896670 hasConceptScore W2734896670C126322002 @default.
- W2734896670 hasConceptScore W2734896670C134018914 @default.
- W2734896670 hasConceptScore W2734896670C15744967 @default.
- W2734896670 hasConceptScore W2734896670C169760540 @default.
- W2734896670 hasConceptScore W2734896670C169900460 @default.
- W2734896670 hasConceptScore W2734896670C170493617 @default.
- W2734896670 hasConceptScore W2734896670C185263204 @default.
- W2734896670 hasConceptScore W2734896670C188987157 @default.
- W2734896670 hasConceptScore W2734896670C24998067 @default.
- W2734896670 hasConceptScore W2734896670C2781195155 @default.
- W2734896670 hasConceptScore W2734896670C71924100 @default.
- W2734896670 hasConceptScore W2734896670C86803240 @default.
- W2734896670 hasLocation W27348966701 @default.
- W2734896670 hasOpenAccess W2734896670 @default.
- W2734896670 hasPrimaryLocation W27348966701 @default.
- W2734896670 hasRelatedWork W1493414555 @default.
- W2734896670 hasRelatedWork W1978905259 @default.
- W2734896670 hasRelatedWork W2000856003 @default.
- W2734896670 hasRelatedWork W2050302780 @default.
- W2734896670 hasRelatedWork W2078626262 @default.
- W2734896670 hasRelatedWork W2085739435 @default.
- W2734896670 hasRelatedWork W2088516418 @default.
- W2734896670 hasRelatedWork W2092072380 @default.
- W2734896670 hasRelatedWork W2100534702 @default.
- W2734896670 hasRelatedWork W2147040438 @default.
- W2734896670 hasRelatedWork W2562899259 @default.
- W2734896670 hasRelatedWork W2793531311 @default.
- W2734896670 hasRelatedWork W2908893760 @default.
- W2734896670 hasRelatedWork W2920463700 @default.
- W2734896670 hasRelatedWork W2979282876 @default.
- W2734896670 hasRelatedWork W3033609536 @default.
- W2734896670 hasRelatedWork W3091687282 @default.
- W2734896670 hasRelatedWork W3185276904 @default.
- W2734896670 hasRelatedWork W2184317571 @default.
- W2734896670 hasRelatedWork W3001250982 @default.
- W2734896670 isParatext "false" @default.
- W2734896670 isRetracted "false" @default.
- W2734896670 magId "2734896670" @default.
- W2734896670 workType "dissertation" @default.