FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2735051785> ?p ?o ?g. }

• W2735051785 abstract "Introduction: Hair health concern is one of the most distressing conditions for a significant number of men and women of all ages. The unique current pharmacologic therapeutic options approved by Food and Drug administration (FDA) are finasteride and topical minoxidil; however, these treatments may have side effects and may work on just one cause of hair loss, without giving an exhaustive and complete results.Objective: The aim of this study was to evaluate the efficacy of a nutritional complex, combining omega 3-6-9, antioxidant, natural inhibitors of 5α-reductase and anti-inflammatory molecules in improving hair loss and hair health parameter such as volume, strength and reduction of greasiness.Methods: This study was made up of two phases. The in vitro experiment aimed at evaluating the capacity of the nutritional complex to lower the enzyme 5α-reductase activity in culture of human keratinocytes. The in vivo study was performed on 30 volunteers who experienced a 6 months treatment with the nutritional complex. The evaluation of hair loss and hair health parameter was performed by trichoscopy, global photograph review and subject’s assessment.Results: The in vitro study showed the capacity of the nutritional formulation to inhibit the total 5α-reductase comparable to finasteride and Serenoa repens. The global photograph assessment at T0 and T6 showed an increased hair density on 83.3% of subjects and the preliminary results were already visible just after three months. Moreover, the trichoscopy demonstrates an increase of hair diameter and hair density, an improvement of vascularization and a reduction of greasiness at the follicle level. The hair quality and hair loss reduction valued by the subjects showed positive results confirming the photographic outcomes.Conclusions: This study proves the action of nutritional complex components, s-sitosterosl with omega 3-6 complex from Serenoa repens, linseed, borage, wheat oils, pine bark and rye grass in inhibition of the total 5α- reductase. Furthermore, both the reduction of hair greasiness and the improvement of hair quality demonstrate that this formulation is not only effective against 5α-reductase but it also exerts its properties in a complete manner by restoring the physiologic condition of a healthy scalp. Moreover, it demonstrates the positive effects of this natural complex supplementation on overall scalp coverage. Visibly there is an improvement of vascularization, hair diameter and the reduction of hair loss perception." @default.
• W2735051785 created "2017-07-21" @default.
• W2735051785 creator A5021760169 @default.
• W2735051785 creator A5048155793 @default.
• W2735051785 creator A5054534489 @default.
• W2735051785 creator A5088421903 @default.
• W2735051785 date "2017-01-01" @default.
• W2735051785 modified "2023-09-27" @default.
• W2735051785 title "Efficacy of a Nutritional Supplement, Standardized in Fatty Acids and Phytosterols, on Hair Loss and Hair Health in both Women and Men" @default.
• W2735051785 cites W1712693945 @default.
• W2735051785 cites W1812642202 @default.
• W2735051785 cites W1966690548 @default.
• W2735051785 cites W1968831702 @default.
• W2735051785 cites W1970913044 @default.
• W2735051785 cites W1985373201 @default.
• W2735051785 cites W1992052182 @default.
• W2735051785 cites W2006064297 @default.
• W2735051785 cites W2027553002 @default.
• W2735051785 cites W2045635893 @default.
• W2735051785 cites W2054117560 @default.
• W2735051785 cites W2056943131 @default.
• W2735051785 cites W2061283723 @default.
• W2735051785 cites W2084566583 @default.
• W2735051785 cites W2092925366 @default.
• W2735051785 cites W2100058126 @default.
• W2735051785 cites W2106061969 @default.
• W2735051785 cites W2124410712 @default.
• W2735051785 cites W2125502478 @default.
• W2735051785 cites W2132718476 @default.
• W2735051785 cites W2138854179 @default.
• W2735051785 cites W2143852270 @default.
• W2735051785 cites W2144744212 @default.
• W2735051785 cites W2156757464 @default.
• W2735051785 cites W2511006924 @default.
• W2735051785 cites W2534750020 @default.
• W2735051785 cites W83300408 @default.
• W2735051785 doi "https://doi.org/10.4172/2471-9323.1000121" @default.
• W2735051785 hasPublicationYear "2017" @default.
• W2735051785 type Work @default.
• W2735051785 sameAs 2735051785 @default.
• W2735051785 citedByCount "3" @default.
• W2735051785 countsByYear W27350517852020 @default.
• W2735051785 countsByYear W27350517852023 @default.
• W2735051785 crossrefType "journal-article" @default.
• W2735051785 hasAuthorship W2735051785A5021760169 @default.
• W2735051785 hasAuthorship W2735051785A5048155793 @default.
• W2735051785 hasAuthorship W2735051785A5054534489 @default.
• W2735051785 hasAuthorship W2735051785A5088421903 @default.
• W2735051785 hasBestOaLocation W27350517851 @default.
• W2735051785 hasConcept C16005928 @default.
• W2735051785 hasConcept C185592680 @default.
• W2735051785 hasConcept C2776360568 @default.
• W2735051785 hasConcept C3018363719 @default.
• W2735051785 hasConcept C3020618081 @default.
• W2735051785 hasConcept C31903555 @default.
• W2735051785 hasConcept C42407357 @default.
• W2735051785 hasConcept C556039675 @default.
• W2735051785 hasConcept C71924100 @default.
• W2735051785 hasConceptScore W2735051785C16005928 @default.
• W2735051785 hasConceptScore W2735051785C185592680 @default.
• W2735051785 hasConceptScore W2735051785C2776360568 @default.
• W2735051785 hasConceptScore W2735051785C3018363719 @default.
• W2735051785 hasConceptScore W2735051785C3020618081 @default.
• W2735051785 hasConceptScore W2735051785C31903555 @default.
• W2735051785 hasConceptScore W2735051785C42407357 @default.
• W2735051785 hasConceptScore W2735051785C556039675 @default.
• W2735051785 hasConceptScore W2735051785C71924100 @default.
• W2735051785 hasIssue "02" @default.
• W2735051785 hasLocation W27350517851 @default.
• W2735051785 hasOpenAccess W2735051785 @default.
• W2735051785 hasPrimaryLocation W27350517851 @default.
• W2735051785 hasRelatedWork W2095086451 @default.
• W2735051785 hasRelatedWork W2305697527 @default.
• W2735051785 hasRelatedWork W2320444539 @default.
• W2735051785 hasRelatedWork W2581020470 @default.
• W2735051785 hasRelatedWork W2754577759 @default.
• W2735051785 hasRelatedWork W2991512285 @default.
• W2735051785 hasRelatedWork W3006200565 @default.
• W2735051785 hasRelatedWork W3119837559 @default.
• W2735051785 hasRelatedWork W2283917414 @default.
• W2735051785 hasRelatedWork W2502378498 @default.
• W2735051785 hasVolume "03" @default.
• W2735051785 isParatext "false" @default.
• W2735051785 isRetracted "false" @default.
• W2735051785 magId "2735051785" @default.
• W2735051785 workType "article" @default.