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- W2735107816 abstract "The clinical findings in liver disorders and viral hepatitis during oral contraceptive use are reviewed. Oral contraceptives induce certain liver enzymes and serum proteins; liver dysfunction may be responsible for nausea headaches and dizziness; jaundice and pruritis in oral contraception is definitely more frequent in women predisposed to cholestasis of pregnancy. In normal women taking the pill bilirubin ornithine-transcarbamylase transaminases Hanger test galactose challenge and BSP retention are sometimes elevated. In cholestatic jaundice during oral contraception conjugated bilirubin cholesterol aklaline phosphatase bile acids transaminases and the capacity to excrete BSP are abnormal. Estrogens are responsible possibly by affecting metabolism or bile flux. Pills are contraindicated in women with prior jaundice in pregnancy Dubin-Johnson syndrome jaundice with a positive lymphoblast transformation test and acute viral hepatitis. The prognosis of viral hepatitis is unaffected by the pill but estrogen excretion may be reduced. After serum enzymes become normal oral contraceptives may be prescribed depending on the severity of the disorder if possible avoiding alkylated C-17 derivatives and estrogens and choosing the dose carefully. It appears that the pill will not cause permanent liver damage but it should be replaced in viral hepatitis by another efficient contraceptive." @default.
- W2735107816 created "2017-07-21" @default.
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- W2735107816 date "1974-01-01" @default.
- W2735107816 modified "2023-09-27" @default.
- W2735107816 title "Hepatitis and oral contraception" @default.
- W2735107816 hasPublicationYear "1974" @default.
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