FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2735832495> ?p ?o ?g. }

• W2735832495 abstract "Background and Purpose: The aim of this study was to systematically review the efficacy and tolerability of gabapentin in the treatment of sleep disturbance in patients with medical illness. Methods: PubMed was searched for randomized, double-blinded, placebo controlled trials that reported sleep changes during gabapentin treatment up to November 2015. Findings: This review included 26 studies involving 4,684 participants. Except for Composite Endpoint 3 (standardized mean difference (SMD)=0.09, 95% confidence interval (CI): -0.05 to 0.22), compared with the placebo group, the gabapentin group showed superior outcomes on our endpoints: Composite Endpoint 1 (SMD=0.50, 95% CI: 0.28 to 0.71), Composite Endpoint 2 (SMD=-0.53, 95% CI: -0.77 to -0.30), Composite Endpoint 4 (SMD=-0.38, 95% CI: -0.58 to -0.19), Composite Endpoint 5 (Risk Ratio (RR)=1.79, 95% CI: 1.24 to 2.58), and Composite Endpoint 6 (RR=0.48, 95% CI: 0.32 to 0.72). However, the patients in the gabapentin group showed worse tolerance than those in the placebo group (RR=1.38, 95% CI: 1.08 to 1.76). Implications: This study is the first to systematically assess the clinical value of gabapentin for the treatment of sleep disorders. We found that regardless the type of sleep outcomes, gabapentin displayed stable treatment efficacy for sleep disturbance in patients with medical illness. However, when an average dose of approximately 1,800 mg/day was used, the risk of treatment discontinuation or drug withdrawal was relatively high. We recommend that further studies confirm these findings in patients with primary sleep disorders." @default.
• W2735832495 created "2017-07-21" @default.
• W2735832495 creator A5008739295 @default.
• W2735832495 creator A5022396416 @default.
• W2735832495 creator A5034838805 @default.
• W2735832495 creator A5045142353 @default.
• W2735832495 creator A5054720265 @default.
• W2735832495 creator A5055942783 @default.
• W2735832495 creator A5081570477 @default.
• W2735832495 date "2017-07-14" @default.
• W2735832495 modified "2023-09-27" @default.
• W2735832495 title "Efficacy and Tolerability of Gabapentin in Adults with Sleep Disturbance in Medical Illness: A Systematic Review and Meta-analysis" @default.
• W2735832495 cites W1547646341 @default.
• W2735832495 cites W1549770276 @default.
• W2735832495 cites W1969725360 @default.
• W2735832495 cites W197066864 @default.
• W2735832495 cites W1975340066 @default.
• W2735832495 cites W1976066489 @default.
• W2735832495 cites W1979309020 @default.
• W2735832495 cites W1988074930 @default.
• W2735832495 cites W1991024180 @default.
• W2735832495 cites W1992956723 @default.
• W2735832495 cites W1999146151 @default.
• W2735832495 cites W1999346159 @default.
• W2735832495 cites W2009137120 @default.
• W2735832495 cites W2012714739 @default.
• W2735832495 cites W2014670473 @default.
• W2735832495 cites W2021124523 @default.
• W2735832495 cites W2033667388 @default.
• W2735832495 cites W2037311654 @default.
• W2735832495 cites W2038648766 @default.
• W2735832495 cites W2039824535 @default.
• W2735832495 cites W2039982019 @default.
• W2735832495 cites W2040749672 @default.
• W2735832495 cites W2046833288 @default.
• W2735832495 cites W2057381230 @default.
• W2735832495 cites W2057983296 @default.
• W2735832495 cites W2060579001 @default.
• W2735832495 cites W2062041648 @default.
• W2735832495 cites W2064914903 @default.
• W2735832495 cites W2065434413 @default.
• W2735832495 cites W2068123007 @default.
• W2735832495 cites W2073170620 @default.
• W2735832495 cites W2075556621 @default.
• W2735832495 cites W2082850379 @default.
• W2735832495 cites W2085662780 @default.
• W2735832495 cites W2086537249 @default.
• W2735832495 cites W2101039973 @default.
• W2735832495 cites W2113077819 @default.
• W2735832495 cites W2121052523 @default.
• W2735832495 cites W2135227200 @default.
• W2735832495 cites W2136403658 @default.
• W2735832495 cites W2151487996 @default.
• W2735832495 cites W2159492208 @default.
• W2735832495 cites W2163350351 @default.
• W2735832495 cites W3022903699 @default.
• W2735832495 cites W4234962147 @default.
• W2735832495 cites W4239281539 @default.
• W2735832495 cites W86291341 @default.
• W2735832495 cites W90317597 @default.
• W2735832495 doi "https://doi.org/10.3389/fneur.2017.00316" @default.
• W2735832495 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5510619" @default.
• W2735832495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28769860" @default.
• W2735832495 hasPublicationYear "2017" @default.
• W2735832495 type Work @default.
• W2735832495 sameAs 2735832495 @default.
• W2735832495 citedByCount "13" @default.
• W2735832495 countsByYear W27358324952018 @default.
• W2735832495 countsByYear W27358324952021 @default.
• W2735832495 countsByYear W27358324952022 @default.
• W2735832495 countsByYear W27358324952023 @default.
• W2735832495 crossrefType "journal-article" @default.
• W2735832495 hasAuthorship W2735832495A5008739295 @default.
• W2735832495 hasAuthorship W2735832495A5022396416 @default.
• W2735832495 hasAuthorship W2735832495A5034838805 @default.
• W2735832495 hasAuthorship W2735832495A5045142353 @default.
• W2735832495 hasAuthorship W2735832495A5054720265 @default.
• W2735832495 hasAuthorship W2735832495A5055942783 @default.
• W2735832495 hasAuthorship W2735832495A5081570477 @default.
• W2735832495 hasBestOaLocation W27358324951 @default.
• W2735832495 hasConcept C118552586 @default.
• W2735832495 hasConcept C126322002 @default.
• W2735832495 hasConcept C142724271 @default.
• W2735832495 hasConcept C1513209611 @default.
• W2735832495 hasConcept C168563851 @default.
• W2735832495 hasConcept C187960798 @default.
• W2735832495 hasConcept C197934379 @default.
• W2735832495 hasConcept C203092338 @default.
• W2735832495 hasConcept C204787440 @default.
• W2735832495 hasConcept C27081682 @default.
• W2735832495 hasConcept C2776608144 @default.
• W2735832495 hasConcept C2778375690 @default.
• W2735832495 hasConcept C2778715236 @default.
• W2735832495 hasConcept C2781210498 @default.
• W2735832495 hasConcept C42219234 @default.
• W2735832495 hasConcept C44249647 @default.
• W2735832495 hasConcept C71924100 @default.
• W2735832495 hasConcept C82789193 @default.
• W2735832495 hasConcept C95190672 @default.
• W2735832495 hasConceptScore W2735832495C118552586 @default.

• next