Matches in SemOpenAlex for { <https://semopenalex.org/work/W2736032406> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2736032406 abstract "Background : C-reactive protein (CRP) and tumor necrosis factor-α(TNF- α) are specific proteins modulated by the acute stress ofsurgery. Various retrospective and prospective studies havedemonstrated subdued stress responses in laparoscopically operatedpatients vis-a-vis the conventional (open) method. Aim : Toassess the roles of TNF- α and C-reactive protein levels astentative stress markers in correlating the extent of perioperativeimmune modulation during open and laparoscopic cholecystectomy in asubset of an Indian population. Setting and Design : This study is aprospective study. Materials and Methods : Forty patients admitted andoperated over a period of two years, were assigned to two groups:laparascopic cholecystectomy (LC) (Group-I) or open cholecystectomy(OC) (Group-II). Selection was based on: patients′ preference,patients′ insistence, patients′ inability to afford thelaparoscopic procedure, lack of expertise or lack of facility in thehospital for the laparoscopic procedure. The baseline characteristicsin terms of anesthetic protocol, fluid management, postoperative ordersand perioperative care were kept similar for both groups. StatisticalAnalysis : SPSS v.11 was used for statistical computations. Results :Baseline values of CRP in the OC and LC Groups were 7.9959 ±5.57837 µg/ml and 11.3948 ± 11.61055 µg/ml respectively.CRP values rose markedly during the intra- as well as the postoperativeperiods till day 4 ( P < 0.001) in both the groups. Intragroupvariations were not significantly different from each other ( P >0.05). No such trend was noticed for TNF-α levels under identicalconditions. Indeed, the TNF-α levels were 2.0304 ± 5.67384pg/ml and 11.3408 ± 25.09385 pg/ml in the OC and LC groupsrespectively. Intragroup changes were not significantly different fromeach other ( P > 0.05). Percentage changes in CRP and TNF-αwere higher after OC in comparison to LC. Conclusions : The presentstudy did not record statistical differences in the levels of the twomarkers (CRP, TNF-α) between the two groups. This reflects thelimited tissue trauma due to easy and simple visceral tissue dissectionin the two types of nondifficult surgery intraoperatively. However,greater change ( P = 0.09) of TNF levels (30% vs. 1.9%) in the OCgroup on the 4 th postoperative day represents the possibility ofgreater immune modulation in the OC group postoperatively." @default.
- W2736032406 created "2017-07-21" @default.
- W2736032406 creator A5030530437 @default.
- W2736032406 creator A5034288554 @default.
- W2736032406 creator A5055094737 @default.
- W2736032406 creator A5065745968 @default.
- W2736032406 creator A5068965424 @default.
- W2736032406 creator A5082533364 @default.
- W2736032406 date "2007-08-28" @default.
- W2736032406 modified "2023-09-24" @default.
- W2736032406 title "Comparative assessment of TNF-α and C-reactive protein in patientssubjected to open instead of laparoscopic cholecystectomy" @default.
- W2736032406 hasPublicationYear "2007" @default.
- W2736032406 type Work @default.
- W2736032406 sameAs 2736032406 @default.
- W2736032406 citedByCount "0" @default.
- W2736032406 crossrefType "journal-article" @default.
- W2736032406 hasAuthorship W2736032406A5030530437 @default.
- W2736032406 hasAuthorship W2736032406A5034288554 @default.
- W2736032406 hasAuthorship W2736032406A5055094737 @default.
- W2736032406 hasAuthorship W2736032406A5065745968 @default.
- W2736032406 hasAuthorship W2736032406A5068965424 @default.
- W2736032406 hasAuthorship W2736032406A5082533364 @default.
- W2736032406 hasConcept C126322002 @default.
- W2736032406 hasConcept C141071460 @default.
- W2736032406 hasConcept C17991360 @default.
- W2736032406 hasConcept C188816634 @default.
- W2736032406 hasConcept C2776098842 @default.
- W2736032406 hasConcept C2776111594 @default.
- W2736032406 hasConcept C2776641081 @default.
- W2736032406 hasConcept C2776914184 @default.
- W2736032406 hasConcept C2780047204 @default.
- W2736032406 hasConcept C2781195455 @default.
- W2736032406 hasConcept C2987287001 @default.
- W2736032406 hasConcept C3020409179 @default.
- W2736032406 hasConcept C31174226 @default.
- W2736032406 hasConcept C71924100 @default.
- W2736032406 hasConcept C90924648 @default.
- W2736032406 hasConceptScore W2736032406C126322002 @default.
- W2736032406 hasConceptScore W2736032406C141071460 @default.
- W2736032406 hasConceptScore W2736032406C17991360 @default.
- W2736032406 hasConceptScore W2736032406C188816634 @default.
- W2736032406 hasConceptScore W2736032406C2776098842 @default.
- W2736032406 hasConceptScore W2736032406C2776111594 @default.
- W2736032406 hasConceptScore W2736032406C2776641081 @default.
- W2736032406 hasConceptScore W2736032406C2776914184 @default.
- W2736032406 hasConceptScore W2736032406C2780047204 @default.
- W2736032406 hasConceptScore W2736032406C2781195455 @default.
- W2736032406 hasConceptScore W2736032406C2987287001 @default.
- W2736032406 hasConceptScore W2736032406C3020409179 @default.
- W2736032406 hasConceptScore W2736032406C31174226 @default.
- W2736032406 hasConceptScore W2736032406C71924100 @default.
- W2736032406 hasConceptScore W2736032406C90924648 @default.
- W2736032406 hasLocation W27360324061 @default.
- W2736032406 hasOpenAccess W2736032406 @default.
- W2736032406 hasPrimaryLocation W27360324061 @default.
- W2736032406 hasRelatedWork W1252452858 @default.
- W2736032406 hasRelatedWork W145721345 @default.
- W2736032406 hasRelatedWork W2013635992 @default.
- W2736032406 hasRelatedWork W2022080102 @default.
- W2736032406 hasRelatedWork W2358442764 @default.
- W2736032406 hasRelatedWork W2362368734 @default.
- W2736032406 hasRelatedWork W2372317336 @default.
- W2736032406 hasRelatedWork W2399507705 @default.
- W2736032406 hasRelatedWork W2463468187 @default.
- W2736032406 hasRelatedWork W2470613247 @default.
- W2736032406 hasRelatedWork W2590472946 @default.
- W2736032406 hasRelatedWork W2801538154 @default.
- W2736032406 hasRelatedWork W2886514611 @default.
- W2736032406 hasRelatedWork W3029114773 @default.
- W2736032406 hasRelatedWork W3030197203 @default.
- W2736032406 hasRelatedWork W3031081585 @default.
- W2736032406 hasRelatedWork W3032309631 @default.
- W2736032406 hasRelatedWork W3033923503 @default.
- W2736032406 hasRelatedWork W3035052254 @default.
- W2736032406 hasRelatedWork W3200993241 @default.
- W2736032406 isParatext "false" @default.
- W2736032406 isRetracted "false" @default.
- W2736032406 magId "2736032406" @default.
- W2736032406 workType "article" @default.