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- W2736144734 abstract "Nanotechnology has facilitated the applications of a class of nanomaterials called superparamagnetic iron oxide nanoparticles (SPIONs) in cancer theranostics. This is a new discipline in biomedicine that combines therapy and diagnosis in one platform. The multifunctional SPIONs, which are capable of detecting, visualizing, and destroying the neoplastic cells with fewer side effects than the conventional therapies, are reviewed in this chapter for theranostic applications. The chapter summarizes the design parameters such as size, shape, coating, and target ligand functionalization of SPIONs, which enhance their ability to diagnose and treat cancer. The review discusses the methods of synthesizing SPIONs, their structural, morphological, and magnetic properties that are important for theranostics. The applications of SPIONs for drug delivery, magnetic resonance imaging, and magnetic hyperthermia therapy (MHT) are included. The results of our recent MHT study on Gd-doped SPION as a possible theranostic agent are highlighted. We have also discussed the challenges and outlook on the future research for theranostics in clinical settings." @default.
- W2736144734 created "2017-07-21" @default.
- W2736144734 creator A5021751631 @default.
- W2736144734 creator A5043614181 @default.
- W2736144734 creator A5065187546 @default.
- W2736144734 creator A5066862953 @default.
- W2736144734 creator A5074414480 @default.
- W2736144734 date "2017-07-12" @default.
- W2736144734 modified "2023-10-13" @default.
- W2736144734 title "Gd-Doped Superparamagnetic Magnetite Nanoparticles for Potential Cancer Theranostics" @default.
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