Matches in SemOpenAlex for { <https://semopenalex.org/work/W2736188889> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2736188889 endingPage "08" @default.
- W2736188889 startingPage "01" @default.
- W2736188889 abstract "Cellular metabolism and bioenergetics are regulated by cancer genes and are intimately linked to the growth and survival of cancer cells. Metabolism generates oxygen radicals, which contribute to oncogenic mutations. Activated oncogenes and loss of tumor suppressors in turn alter metabolism and induce aerobic glycolysis. Aerobic glycolysis or the Warburg effect links the high rate of glucose fermentation to cancer. Together with glutamine, glucose via glycolysis provides the carbon skeletons, NADPH, and ATP to build new cancer cells, which persist in hypoxia that in turn rewires metabolic pathways for cell growth and survival. Excessive caloric intake is associated with an increased risk for cancers, while caloric restriction is protective, perhaps through clearance of mitochondria or mitophagy, thereby reducing oxidative stress. Hence, the links between metabolism and cancer are multifaceted, spanning from the low incidence of cancer in large mammals with low specific metabolic rates to altered cancer cell metabolism resulting from mutated enzymes or cancer genes." @default.
- W2736188889 created "2017-07-21" @default.
- W2736188889 creator A5002664516 @default.
- W2736188889 creator A5006632341 @default.
- W2736188889 creator A5015271317 @default.
- W2736188889 creator A5029468965 @default.
- W2736188889 creator A5063942147 @default.
- W2736188889 date "2016-05-01" @default.
- W2736188889 modified "2023-09-27" @default.
- W2736188889 title "Egfr Augments Aerobic Glycolysis In Multi-Negetive Breast Cancer Cells to Promote Tumorigenesis and Immune Escape" @default.
- W2736188889 hasPublicationYear "2016" @default.
- W2736188889 type Work @default.
- W2736188889 sameAs 2736188889 @default.
- W2736188889 citedByCount "0" @default.
- W2736188889 crossrefType "journal-article" @default.
- W2736188889 hasAuthorship W2736188889A5002664516 @default.
- W2736188889 hasAuthorship W2736188889A5006632341 @default.
- W2736188889 hasAuthorship W2736188889A5015271317 @default.
- W2736188889 hasAuthorship W2736188889A5029468965 @default.
- W2736188889 hasAuthorship W2736188889A5063942147 @default.
- W2736188889 hasConcept C100206155 @default.
- W2736188889 hasConcept C109156525 @default.
- W2736188889 hasConcept C121608353 @default.
- W2736188889 hasConcept C20251656 @default.
- W2736188889 hasConcept C28859421 @default.
- W2736188889 hasConcept C502942594 @default.
- W2736188889 hasConcept C54355233 @default.
- W2736188889 hasConcept C55493867 @default.
- W2736188889 hasConcept C555283112 @default.
- W2736188889 hasConcept C55885012 @default.
- W2736188889 hasConcept C57600042 @default.
- W2736188889 hasConcept C62231903 @default.
- W2736188889 hasConcept C66517615 @default.
- W2736188889 hasConcept C86803240 @default.
- W2736188889 hasConcept C95444343 @default.
- W2736188889 hasConcept C96232424 @default.
- W2736188889 hasConceptScore W2736188889C100206155 @default.
- W2736188889 hasConceptScore W2736188889C109156525 @default.
- W2736188889 hasConceptScore W2736188889C121608353 @default.
- W2736188889 hasConceptScore W2736188889C20251656 @default.
- W2736188889 hasConceptScore W2736188889C28859421 @default.
- W2736188889 hasConceptScore W2736188889C502942594 @default.
- W2736188889 hasConceptScore W2736188889C54355233 @default.
- W2736188889 hasConceptScore W2736188889C55493867 @default.
- W2736188889 hasConceptScore W2736188889C555283112 @default.
- W2736188889 hasConceptScore W2736188889C55885012 @default.
- W2736188889 hasConceptScore W2736188889C57600042 @default.
- W2736188889 hasConceptScore W2736188889C62231903 @default.
- W2736188889 hasConceptScore W2736188889C66517615 @default.
- W2736188889 hasConceptScore W2736188889C86803240 @default.
- W2736188889 hasConceptScore W2736188889C95444343 @default.
- W2736188889 hasConceptScore W2736188889C96232424 @default.
- W2736188889 hasIssue "5" @default.
- W2736188889 hasLocation W27361888891 @default.
- W2736188889 hasOpenAccess W2736188889 @default.
- W2736188889 hasPrimaryLocation W27361888891 @default.
- W2736188889 hasRelatedWork W106917877 @default.
- W2736188889 hasRelatedWork W161777538 @default.
- W2736188889 hasRelatedWork W2056444349 @default.
- W2736188889 hasRelatedWork W2105665764 @default.
- W2736188889 hasRelatedWork W2211830473 @default.
- W2736188889 hasRelatedWork W2391692482 @default.
- W2736188889 hasRelatedWork W2511602275 @default.
- W2736188889 hasRelatedWork W2777685881 @default.
- W2736188889 hasRelatedWork W2790419205 @default.
- W2736188889 hasRelatedWork W2891404117 @default.
- W2736188889 hasRelatedWork W2913186781 @default.
- W2736188889 hasRelatedWork W2915774090 @default.
- W2736188889 hasRelatedWork W2957270451 @default.
- W2736188889 hasRelatedWork W2965102054 @default.
- W2736188889 hasRelatedWork W3005735687 @default.
- W2736188889 hasRelatedWork W3005918052 @default.
- W2736188889 hasRelatedWork W3015481613 @default.
- W2736188889 hasRelatedWork W3031582462 @default.
- W2736188889 hasRelatedWork W3158660301 @default.
- W2736188889 hasRelatedWork W3195956767 @default.
- W2736188889 hasVolume "5" @default.
- W2736188889 isParatext "false" @default.
- W2736188889 isRetracted "false" @default.
- W2736188889 magId "2736188889" @default.
- W2736188889 workType "article" @default.