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• W2736218704 abstract "Chronic Pseudomonas aeruginosa lung infection is the cause of much morbidity and most of the mortality in cystic fibrosis (CF) patients. The high prevalence of P. aeruginosa infections in CF is related to the microbe's large genome and mechanisms of adaptation to the CF lung environment, the host immune system and antibiotic resistance. Among a wide range of P. aeruginosa metabolites involved in infection development in CF, the biosurfactant compounds, rhamnolipids (RLs) and exopolysaccharides (EPSs), have important roles in the early stages of P. aeruginosa infection in CF. RLs and EPSs are involved in bacterial adhesion, biofilm formation, antibiotic resistance, and impairment of host immune system pathways, as well as in processes such as biofilm maintenance and the mucoid phenotype of P. aeruginosa, which lead to development of chronic infection. Due to the proposed roles of RLs and EPSs and the importance of prevention and treatment of P. aeruginosa respiratory infections in CF, these compounds are promising targets for patient therapy. In the future, impairment of P. aeruginosa quorum sensing (QS) pathways and modification of host respiratory mucus epithelial membranes should be considered as potential approaches in preventing respiratory infections caused by this microbe in CF patients." @default.
• W2736218704 created "2017-07-21" @default.
• W2736218704 creator A5025759806 @default.
• W2736218704 creator A5086370653 @default.
• W2736218704 creator A5086723837 @default.
• W2736218704 date "2017-07-12" @default.
• W2736218704 modified "2023-10-16" @default.
• W2736218704 title "Structure‐Function Relationships of Rhamnolipid and Exopolysacharide Biosurfactants of Pseudomonas aeruginosa as Therapeutic Targets in Cystic Fibrosis Lung Infections" @default.
• W2736218704 cites W134674384 @default.
• W2736218704 cites W1497309636 @default.
• W2736218704 cites W1526671744 @default.
• W2736218704 cites W1557995667 @default.
• W2736218704 cites W1563717395 @default.
• W2736218704 cites W1574740692 @default.
• W2736218704 cites W1578449205 @default.
• W2736218704 cites W1680383394 @default.
• W2736218704 cites W1884050056 @default.
• W2736218704 cites W1903793119 @default.
• W2736218704 cites W1907600034 @default.
• W2736218704 cites W1939060006 @default.
• W2736218704 cites W1962049618 @default.
• W2736218704 cites W1964957585 @default.
• W2736218704 cites W1965538842 @default.
• W2736218704 cites W1966552407 @default.
• W2736218704 cites W1967398861 @default.
• W2736218704 cites W1969537603 @default.
• W2736218704 cites W1969761542 @default.
• W2736218704 cites W1976247790 @default.
• W2736218704 cites W1976789457 @default.
• W2736218704 cites W1979152503 @default.
• W2736218704 cites W1981428780 @default.
• W2736218704 cites W1983225740 @default.
• W2736218704 cites W1983262214 @default.
• W2736218704 cites W1985687704 @default.
• W2736218704 cites W1990591441 @default.
• W2736218704 cites W1991795415 @default.
• W2736218704 cites W1991993699 @default.
• W2736218704 cites W1993513102 @default.
• W2736218704 cites W1997637703 @default.
• W2736218704 cites W2002059197 @default.
• W2736218704 cites W2003627983 @default.
• W2736218704 cites W2004333368 @default.
• W2736218704 cites W2006828391 @default.
• W2736218704 cites W2007002493 @default.
• W2736218704 cites W2008020809 @default.
• W2736218704 cites W2008471111 @default.
• W2736218704 cites W2014165289 @default.
• W2736218704 cites W2015935547 @default.
• W2736218704 cites W2017603080 @default.
• W2736218704 cites W2021361246 @default.
• W2736218704 cites W2021376949 @default.
• W2736218704 cites W2022634662 @default.
• W2736218704 cites W2023693474 @default.
• W2736218704 cites W2024207645 @default.
• W2736218704 cites W2024534479 @default.
• W2736218704 cites W2030322773 @default.
• W2736218704 cites W2030500704 @default.
• W2736218704 cites W2031552167 @default.
• W2736218704 cites W2034084330 @default.
• W2736218704 cites W2034358674 @default.
• W2736218704 cites W2037199202 @default.
• W2736218704 cites W2038131854 @default.
• W2736218704 cites W2038404933 @default.
• W2736218704 cites W2039104003 @default.
• W2736218704 cites W2040005036 @default.
• W2736218704 cites W2041051698 @default.
• W2736218704 cites W2044876834 @default.
• W2736218704 cites W2046036915 @default.
• W2736218704 cites W2049652196 @default.
• W2736218704 cites W2051359722 @default.
• W2736218704 cites W2055261049 @default.
• W2736218704 cites W2055753580 @default.
• W2736218704 cites W2055767311 @default.
• W2736218704 cites W2055857822 @default.
• W2736218704 cites W2056064659 @default.
• W2736218704 cites W2057418340 @default.
• W2736218704 cites W2058603691 @default.
• W2736218704 cites W2058650458 @default.
• W2736218704 cites W2059953204 @default.
• W2736218704 cites W2062906311 @default.
• W2736218704 cites W2067252525 @default.
• W2736218704 cites W2068482259 @default.
• W2736218704 cites W2069814295 @default.
• W2736218704 cites W2071283445 @default.
• W2736218704 cites W2073233593 @default.
• W2736218704 cites W2078895028 @default.
• W2736218704 cites W2079338771 @default.
• W2736218704 cites W2079698171 @default.
• W2736218704 cites W2083456954 @default.
• W2736218704 cites W2084235320 @default.
• W2736218704 cites W2089606209 @default.
• W2736218704 cites W2094044860 @default.
• W2736218704 cites W2096121963 @default.
• W2736218704 cites W2096797367 @default.
• W2736218704 cites W2096911199 @default.
• W2736218704 cites W2100619015 @default.
• W2736218704 cites W2100669918 @default.
• W2736218704 cites W2102677849 @default.
• W2736218704 cites W2103780237 @default.
• W2736218704 cites W2106351298 @default.

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