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- W2736229519 abstract "Abstract The dynamics of blood fluorescence (FL) after intravenous injection of 5-fluorouracil (FU) to oncology patients taking chemotherapy were investigated. It was demonstrated that FU quenches FL of water solutions of tryptophan (Trp) (total concentration is 1.0 × 10 −5 mol L −1 , λ max = 353 nm) and plasma protein – albumin ( λ max = 340 nm) with the Stern–Volmer constants 16.4 × 10 3 L mol −1 and 52 L mol −1 , accordingly. The quenching of both Trp and albumin FL by 5-fluorouracil was concluded to proceed via the static mechanism of reversible photoinduced electron transfer (PET)." @default.
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- W2736229519 date "2017-12-01" @default.
- W2736229519 modified "2023-09-27" @default.
- W2736229519 title "The «in vivo» study of blood 5-fluorouracil content by quenching of intrinsic protein fluorescence" @default.
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- W2736229519 doi "https://doi.org/10.1016/j.jlumin.2017.07.023" @default.
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