Matches in SemOpenAlex for { <https://semopenalex.org/work/W2736624008> ?p ?o ?g. }
- W2736624008 endingPage "15" @default.
- W2736624008 startingPage "2" @default.
- W2736624008 abstract "Class 1 level A evidence now supports endovascular thrombectomy as best practice in the management of large vessel occlusion acute ischaemic stroke. However, significant questions pertaining to initial imaging, radiological assessment, patient selection and therapeutic limits remain unanswered. A specific cohort of patients who benefit from endovascular thrombectomy has been established, although current uncertainties regarding selection of those not meeting top-tier evidence criteria may potentially deny certain patients the benefit of intervention. This is of particular relevance in patients presenting in a delayed manner. Whilst superior outcomes are achieved with reduced time to endovascular reperfusion, denying patients intervention based on symptom duration alone may not be appropriate. Advanced understanding of ischaemic stroke pathophysiology supports an individualized approach to patient evaluation, given variance in the rate of ischaemic core progression and the extent of salvageable penumbra. Physiological imaging techniques may therefore be utilized to better inform patient selection for endovascular thrombectomy and evidence suggests that a transition from time-based to tissue-based therapeutic thresholds may be of greater value. Multiple ongoing randomized controlled trials aim to further define the benefit of endovascular thrombectomy and it is hoped that these results will advance, and possibly broaden, patient selection criteria to ensure that maximum benefit from the intervention may be achieved." @default.
- W2736624008 created "2017-07-31" @default.
- W2736624008 creator A5012120918 @default.
- W2736624008 creator A5015260486 @default.
- W2736624008 creator A5041590267 @default.
- W2736624008 creator A5058470837 @default.
- W2736624008 creator A5085540962 @default.
- W2736624008 date "2017-09-21" @default.
- W2736624008 modified "2023-09-27" @default.
- W2736624008 title "Current evidence for endovascular therapy in stroke and remaining uncertainties" @default.
- W2736624008 cites W1595283758 @default.
- W2736624008 cites W1604965699 @default.
- W2736624008 cites W1721061675 @default.
- W2736624008 cites W1909935856 @default.
- W2736624008 cites W1932494896 @default.
- W2736624008 cites W1973648711 @default.
- W2736624008 cites W1974258435 @default.
- W2736624008 cites W1978104126 @default.
- W2736624008 cites W1988591730 @default.
- W2736624008 cites W1990814258 @default.
- W2736624008 cites W1996667632 @default.
- W2736624008 cites W1997064745 @default.
- W2736624008 cites W2000658246 @default.
- W2736624008 cites W2007958292 @default.
- W2736624008 cites W2013317331 @default.
- W2736624008 cites W2014796100 @default.
- W2736624008 cites W2018504229 @default.
- W2736624008 cites W2019002603 @default.
- W2736624008 cites W2019099022 @default.
- W2736624008 cites W2036653122 @default.
- W2736624008 cites W2037233673 @default.
- W2736624008 cites W2037399775 @default.
- W2736624008 cites W2038422976 @default.
- W2736624008 cites W2046671107 @default.
- W2736624008 cites W2051762050 @default.
- W2736624008 cites W2052221403 @default.
- W2736624008 cites W2068321480 @default.
- W2736624008 cites W2074244299 @default.
- W2736624008 cites W2074783305 @default.
- W2736624008 cites W2077131483 @default.
- W2736624008 cites W2086121111 @default.
- W2736624008 cites W2087479972 @default.
- W2736624008 cites W2089157710 @default.
- W2736624008 cites W2107741047 @default.
- W2736624008 cites W2111559905 @default.
- W2736624008 cites W2112392036 @default.
- W2736624008 cites W2114603310 @default.
- W2736624008 cites W2118738743 @default.
- W2736624008 cites W2119542322 @default.
- W2736624008 cites W2120907478 @default.
- W2736624008 cites W2121300729 @default.
- W2736624008 cites W2123472957 @default.
- W2736624008 cites W2124592478 @default.
- W2736624008 cites W2124647721 @default.
- W2736624008 cites W2125404756 @default.
- W2736624008 cites W2127923693 @default.
- W2736624008 cites W2132305654 @default.
- W2736624008 cites W2133514192 @default.
- W2736624008 cites W2134066226 @default.
- W2736624008 cites W2139621750 @default.
- W2736624008 cites W2139703299 @default.
- W2736624008 cites W2142121330 @default.
- W2736624008 cites W2143152026 @default.
- W2736624008 cites W2143237216 @default.
- W2736624008 cites W2144377991 @default.
- W2736624008 cites W2144953162 @default.
- W2736624008 cites W2146307187 @default.
- W2736624008 cites W2148656951 @default.
- W2736624008 cites W2153664287 @default.
- W2736624008 cites W2154303422 @default.
- W2736624008 cites W2155447978 @default.
- W2736624008 cites W2159233098 @default.
- W2736624008 cites W2162134108 @default.
- W2736624008 cites W2165568749 @default.
- W2736624008 cites W2171058244 @default.
- W2736624008 cites W2176628039 @default.
- W2736624008 cites W2198398064 @default.
- W2736624008 cites W2232970024 @default.
- W2736624008 cites W2262744623 @default.
- W2736624008 cites W2277258071 @default.
- W2736624008 cites W2280648452 @default.
- W2736624008 cites W2281174606 @default.
- W2736624008 cites W2303559484 @default.
- W2736624008 cites W2312601012 @default.
- W2736624008 cites W2316593535 @default.
- W2736624008 cites W2324357454 @default.
- W2736624008 cites W2324546810 @default.
- W2736624008 cites W2340148706 @default.
- W2736624008 cites W2340716980 @default.
- W2736624008 cites W2343051183 @default.
- W2736624008 cites W2345730171 @default.
- W2736624008 cites W2399155639 @default.
- W2736624008 cites W2475487380 @default.
- W2736624008 cites W2511388967 @default.
- W2736624008 cites W2526978419 @default.
- W2736624008 cites W2530983624 @default.
- W2736624008 cites W2535348557 @default.
- W2736624008 cites W2556505808 @default.